Erosive potential of children's chewable vitamin supplements: An in vitro investigation.

Q4 Dentistry Journal of Dental Research, Dental Clinics, Dental Prospects Pub Date : 2024-01-01 Epub Date: 2024-12-14 DOI:10.34172/joddd.41791
Wannee Lertsooksawat, Yanisa Tanjaruphan, Thanawat Chaima, Thanawat Lerdpibulchai, Tanawan Wittayathawornwong, Chayada Teanchai, Rudee Surarit, Sivaporn Horsophonphong
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Abstract

Background: Chewable vitamins are dietary supplements in which vitamins are combined with a flavor that appeals to children. The acidic nature of some vitamins and some flavoring agents may cause dental erosion. We investigated the effect of children's chewable vitamin supplements on the loss of minerals in teeth.

Methods: Forty-two human tooth enamel samples were prepared and randomly assigned to seven groups (n=6). Six groups contained different chewable vitamin tablets dissolved in deionized water, and a control group contained only deionized water. Each tablet was ground before its dissolution, and its pH was measured. Each tooth sample was immersed in a vitamin solution and artificial saliva in periodic cycles for 14 days. Each sample was weighed before and after immersion to calculate its weight loss percentage. Scanning electron microscopy was used to investigate the morphology of the enamel surfaces. For statistical analysis, the weight loss percentages between groups were compared using Welch's ANOVA, followed by post hoc Dunnett's T3 analysis (P<0.05).

Results: All the tested supplements were acidic, with a pH range of 2.99‒4.77. Most of the vitamin groups tested led to significant weight loss; it was greater for the vitamin C groups than the multivitamin groups. Scanning electron microscopy revealed erosion and destruction of enamel surfaces following vitamin exposure.

Conclusion: All the chewable vitamin supplements were acidic, with the majority potentially eroding enamel. The erosive potential was less pronounced in vitamin supplements containing minerals.

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儿童可咀嚼维生素补充剂的腐蚀潜力:一项体外研究。
背景:咀嚼维生素是一种膳食补充剂,其中的维生素与一种吸引儿童的味道相结合。一些维生素和调味剂的酸性可能会导致牙齿腐蚀。我们研究了儿童可咀嚼维生素补充剂对牙齿中矿物质流失的影响。方法:制备人牙釉质样品42份,随机分为7组(n=6)。六组服用溶解在去离子水中的不同咀嚼维生素片,对照组只服用去离子水。每片在溶解前研磨,并测量其pH值。每个牙齿样本在维生素溶液和人工唾液中周期性浸泡14天。每个样品浸泡前后称重,计算其失重百分比。用扫描电镜观察牙釉质表面形态。为了进行统计分析,使用Welch's方差分析比较各组之间的体重减轻百分比,然后使用事后Dunnett's T3分析(结果:所有测试的补充剂都是酸性的,pH值范围为2.99-4.77。接受测试的大多数维生素组都能显著减轻体重;维生素C组比多种维生素组更明显。扫描电子显微镜显示维生素暴露后牙釉质表面腐蚀和破坏。结论:所有可咀嚼维生素补充剂均呈酸性,多数具有潜在的牙釉质腐蚀作用。在含有矿物质的维生素补充剂中,侵蚀潜力不那么明显。
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
23
审稿时长
25 weeks
期刊介绍: Journal of Dental Research Dental Clinics Dental Prospects (JODDD) is a Platinum* Open Access, peer-reviewed quarterly indexed journal that publishes articles of basic, clinical, and prospective nature in all areas of dentistry and oral health.
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