Megan Gorman , Vanessa Ross , Lisa dos Santos , Shaza Al-Atassi , Marina Frimer
{"title":"Rectal carcinoma presenting as vulvar metastasis: A case report","authors":"Megan Gorman , Vanessa Ross , Lisa dos Santos , Shaza Al-Atassi , Marina Frimer","doi":"10.1016/j.gore.2025.101681","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Metastatic adenocarcinoma to the vulva is a rare phenomenon, with few cases reported in the literature. Here we discuss a 64-year-old woman with a history of colorectal adenocarcinoma presenting with a vulvar metastasis.</div></div><div><h3>Methods</h3><div>Clinical information was gathered via review of the electronic medical record.</div></div><div><h3>Results</h3><div>IHC is useful in diagnosis of unusual metastases. In this case, staining for CDx2, CK20, PAX8, and CK7 was helpful in distinguishing a gynecologic versus gastrointestinal primary.</div></div><div><h3>Conclusion</h3><div>Our case highlights the importance of an accurate and timely diagnosis of gynecologic metastases in patients with a history of colorectal cancer. Examiners should have a low threshold for biopsy and imaging when patients present with skin changes or vulvovaginal complaints. Appropriate treatment requires a multidisciplinary approach.</div></div>","PeriodicalId":12873,"journal":{"name":"Gynecologic Oncology Reports","volume":"57 ","pages":"Article 101681"},"PeriodicalIF":1.2000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787663/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gynecologic Oncology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352578925000062","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
Metastatic adenocarcinoma to the vulva is a rare phenomenon, with few cases reported in the literature. Here we discuss a 64-year-old woman with a history of colorectal adenocarcinoma presenting with a vulvar metastasis.
Methods
Clinical information was gathered via review of the electronic medical record.
Results
IHC is useful in diagnosis of unusual metastases. In this case, staining for CDx2, CK20, PAX8, and CK7 was helpful in distinguishing a gynecologic versus gastrointestinal primary.
Conclusion
Our case highlights the importance of an accurate and timely diagnosis of gynecologic metastases in patients with a history of colorectal cancer. Examiners should have a low threshold for biopsy and imaging when patients present with skin changes or vulvovaginal complaints. Appropriate treatment requires a multidisciplinary approach.
期刊介绍:
Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.