Rectal carcinoma presenting as vulvar metastasis: A case report

IF 1.3 Q3 OBSTETRICS & GYNECOLOGY Gynecologic Oncology Reports Pub Date : 2025-02-01 Epub Date: 2025-01-17 DOI:10.1016/j.gore.2025.101681
Megan Gorman , Vanessa Ross , Lisa dos Santos , Shaza Al-Atassi , Marina Frimer
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Abstract

Introduction

Metastatic adenocarcinoma to the vulva is a rare phenomenon, with few cases reported in the literature. Here we discuss a 64-year-old woman with a history of colorectal adenocarcinoma presenting with a vulvar metastasis.

Methods

Clinical information was gathered via review of the electronic medical record.

Results

IHC is useful in diagnosis of unusual metastases. In this case, staining for CDx2, CK20, PAX8, and CK7 was helpful in distinguishing a gynecologic versus gastrointestinal primary.

Conclusion

Our case highlights the importance of an accurate and timely diagnosis of gynecologic metastases in patients with a history of colorectal cancer. Examiners should have a low threshold for biopsy and imaging when patients present with skin changes or vulvovaginal complaints. Appropriate treatment requires a multidisciplinary approach.

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直肠癌表现为外阴转移1例。
外阴转移性腺癌是一种罕见的现象,文献报道的病例很少。我们在此讨论一位64岁女性,有结直肠腺癌病史,并表现为外阴转移。方法:通过查阅电子病历收集临床资料。结果:免疫组化对异常转移瘤的诊断有重要意义。在本例中,CDx2、CK20、PAX8和CK7染色有助于区分妇科与胃肠道原发灶。结论:我们的病例强调了准确和及时诊断有结直肠癌病史的患者妇科转移的重要性。当患者出现皮肤变化或外阴阴道不适时,检查人员应该有较低的活检和影像学阈值。适当的治疗需要多学科的方法。
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来源期刊
Gynecologic Oncology Reports
Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-
CiteScore
2.00
自引率
0.00%
发文量
183
审稿时长
41 days
期刊介绍: Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.
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