{"title":"Human amniotic membrane plug to treat failed and highly myopic macular holes. Our experience.","authors":"L Gutierrez-Benitez, G Biarge, M Asaad, B Delas","doi":"10.1016/j.oftale.2025.01.013","DOIUrl":null,"url":null,"abstract":"<p><p>The amniotic membrane (hAM) plug is a treatment option for patients with large refractory or myopic macular holes (MH). The aim of this retrospective case series is to present the anatomical and functional changes during their follow-up that ranges from 10 to 45 months. Out of the ten eyes enrolled, 6 were idiopathic MH and 4 were myopic MH. Notably, 3 of the myopic MH cases were further complicated by posterior pole retinal detachment. Remarkably, 3 patients improved their best-corrected visual acuity, 5 mantained it and 2 worsened it. All the MH closed. Over this period, three instances of hAM plug misplacement following gas absorption required a secondary surgery employing another hAM. In conclusion, the hAM plug seems to be a safe technique and a treatment option for these patients. Further investigations are needed to comprehensively understand the long-term effects of hAM on the retina.</p>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivos de la Sociedad Espanola de Oftalmologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.oftale.2025.01.013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The amniotic membrane (hAM) plug is a treatment option for patients with large refractory or myopic macular holes (MH). The aim of this retrospective case series is to present the anatomical and functional changes during their follow-up that ranges from 10 to 45 months. Out of the ten eyes enrolled, 6 were idiopathic MH and 4 were myopic MH. Notably, 3 of the myopic MH cases were further complicated by posterior pole retinal detachment. Remarkably, 3 patients improved their best-corrected visual acuity, 5 mantained it and 2 worsened it. All the MH closed. Over this period, three instances of hAM plug misplacement following gas absorption required a secondary surgery employing another hAM. In conclusion, the hAM plug seems to be a safe technique and a treatment option for these patients. Further investigations are needed to comprehensively understand the long-term effects of hAM on the retina.
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