A non-enzymatic glucose sensor construct from 3D core-shell structure of NiCo layered double hydroxide coated Ag nanowires based on screen printing electrode

Abstract

Monitoring the glucose concentration in blood makes a great difference on diabetes diagnosis. Herein, we successfully fabricated a kind of 3D hierarchical structure which is NiCo-LDH nanoflower interconnected around Ag nanowires (NiCo-LDH@Ag NWs). The hierarchical core–shell structure offers a large specific surface area and exposing more catalytic sites for electrocatalysis which is benefit for glucose sensing The NiCo-LDH@Ag NWs was dispersed in nafion and modified on screen printing electrode (SPE) to develop portable sensor which marked as NiCo-LDH@Ag NWs/SPE. The as-prepared sensor presents outstanding electrocatalytic ability towards glucose oxidation, including a large detection scale range from 5 μM to 4.5 mM, a sensitivity of 0.52 μA/μM/cm², fast amperometric response/recovery time of 7/7s, good selective, as well as long-time stability. A portable sensing setup, integrating the prepared sensor with a portable potentiostat and smartphone, has been developed. The experimental findings underscore the high performance of the NiCo-LDH@Ag NWs/SPE sensor within this compact detection framework.