Flexible, surface-lighting MicroLED skin patch for multiple human skincare

IF 12.9 1区医学 Q1 ENGINEERING, BIOMEDICAL Biomaterials Pub Date : 2025-07-01 Epub Date: 2025-01-25 DOI:10.1016/j.biomaterials.2025.123139

Jae Hee Lee , Min Seo Kim , Seung Hyung Lee , Sang Hyun Park , Ki Yun Nam , Jaehun An , Myoung Song , Ki Soo Kim , Sang Ho Oh , Taek-Soo Kim , Keon Jae Lee

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Abstract

As the global population ages, concerns regarding aesthetic appearance have increased. Wearable light-emitting diode (LED) devices have received significant attention in the cosmetic fields due to their non-invasive, non-thermal, home-use characteristics. However, conventional bulk LED chips have limitations in flexibility and uniform irradiation, hindering efficient light penetration into the skin. Here, we introduce a flexible, surface-lighting microLED (FSLED) patch with uniform light-emission for various skincare applications. The FSLED was fabricated using a pick-and-place transfer technique, which allows for high-density irradiation over the large area, while maintaining outstanding mechanical flexibility. In addition, the FSLED was designed to deliver light efficiently and emit light evenly by conforming to the skin. Finally, we prove the effect of the FSLED for pore tightening and skin rejuvenation through clinical trials.

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灵活的，表面照明MicroLED皮肤贴片，适用于多种人体皮肤护理

随着全球人口老龄化，人们对外貌的关注也在增加。可穿戴式发光二极管（LED）器件以其无创、无热、家用等特点在化妆品领域受到广泛关注。然而，传统的大块LED芯片在灵活性和均匀照射方面存在局限性，阻碍了有效的光线穿透皮肤。在这里，我们介绍了一种灵活的，表面照明的微led （FSLED）贴片，具有均匀的发光，可用于各种护肤应用。FSLED是使用拾取-放置转移技术制造的，该技术允许在大面积上进行高密度照射，同时保持出色的机械灵活性。此外，FSLED被设计成有效地传递光，并通过符合皮肤均匀发光。最后，我们通过临床试验证明了FSLED对毛孔收缩和皮肤年轻化的效果。

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来源期刊

Biomaterials 工程技术-材料科学：生物材料

CiteScore

26.00

自引率

2.90%

发文量

565

审稿时长

46 days

期刊介绍： Biomaterials is an international journal covering the science and clinical application of biomaterials. A biomaterial is now defined as a substance that has been engineered to take a form which, alone or as part of a complex system, is used to direct, by control of interactions with components of living systems, the course of any therapeutic or diagnostic procedure. It is the aim of the journal to provide a peer-reviewed forum for the publication of original papers and authoritative review and opinion papers dealing with the most important issues facing the use of biomaterials in clinical practice. The scope of the journal covers the wide range of physical, biological and chemical sciences that underpin the design of biomaterials and the clinical disciplines in which they are used. These sciences include polymer synthesis and characterization, drug and gene vector design, the biology of the host response, immunology and toxicology and self assembly at the nanoscale. Clinical applications include the therapies of medical technology and regenerative medicine in all clinical disciplines, and diagnostic systems that reply on innovative contrast and sensing agents. The journal is relevant to areas such as cancer diagnosis and therapy, implantable devices, drug delivery systems, gene vectors, bionanotechnology and tissue engineering.