Merih Cetinkaya , Esin Koc , Betul Acunas , Mete Akisu , Saadet Arsan , Fuat Emre Canpolat , Dilek Dilli , Zeynep Ince , Nilgun Koksal , Abdullah Kumral , Eren Ozek , Hasan Ozkan , Ayse Korkmaz Toygar , Sule Yigit , Aysegul Zenciroglu , Mehmet Vural
{"title":"Turkish Neonatal Society position paper for stem cell therapy in neonates","authors":"Merih Cetinkaya , Esin Koc , Betul Acunas , Mete Akisu , Saadet Arsan , Fuat Emre Canpolat , Dilek Dilli , Zeynep Ince , Nilgun Koksal , Abdullah Kumral , Eren Ozek , Hasan Ozkan , Ayse Korkmaz Toygar , Sule Yigit , Aysegul Zenciroglu , Mehmet Vural","doi":"10.1016/j.gpeds.2024.100239","DOIUrl":null,"url":null,"abstract":"<div><div>Stem cell (SC) therapy has been proposed as a promising therapeutic modality in neonatology, especially for prevention and/or treatment of several interactable diseases such as bronchopulmonary dysplasia, intraventricular hemorrhage, hypoxic-ischemic encephalopathy and others. However, there are several uncertainities in terms of indications, timing, dosage, and safety of SC therapy for routine clinical use in neonates. Herein, a group of Turkish Neonatal Society members evaluated the systematic reviews, meta-analyses, clinical and experimental studies and also case-reports in the literature about the usage of SC therapy in neonatal diseases.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100239"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global pediatrics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667009724001088","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Stem cell (SC) therapy has been proposed as a promising therapeutic modality in neonatology, especially for prevention and/or treatment of several interactable diseases such as bronchopulmonary dysplasia, intraventricular hemorrhage, hypoxic-ischemic encephalopathy and others. However, there are several uncertainities in terms of indications, timing, dosage, and safety of SC therapy for routine clinical use in neonates. Herein, a group of Turkish Neonatal Society members evaluated the systematic reviews, meta-analyses, clinical and experimental studies and also case-reports in the literature about the usage of SC therapy in neonatal diseases.
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