Comparative analysis of mental health in middle-aged women with type-2 diabetes mellitus and hypothyroidism: A cross-sectional study

IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Clinical Epidemiology and Global Health Pub Date : 2025-01-17 DOI:10.1016/j.cegh.2024.101911
Rabia Aziz , Sohrab Ahmad Khan , Sumbul Ansari , Firdaus Jawed
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Abstract

Background

Non-communicable diseases like hypothyroidism and type-2 diabetes mellitus are becoming increasingly prevalent and can lead to anxiety, depression, and memory problems. These mental health comorbidities often go undiagnosed despite significantly impacting quality of life. Sex differences are also observed, with women experiencing higher rates of both conditions.

Objectives

This study aimed to compare the levels of anxiety, depression, and memory in middle-aged women with hypothyroidism and type-2 diabetes mellitus.

Methods

This cross-sectional design recruited 243 females from Hakeem Abdul Hameed Centenary Hospital in New Delhi. Participants were divided into hypothyroidism and type-2 diabetes mellitus groups based on confirmed diagnoses. Questionnaires were used to assess anxiety (GAD-7), depression (PHQ-9), and memory (PGI-memory). Data analysis employed independent-sample t-tests and chi-square tests.

Results

Significant differences (p < 0.05) emerged in mean mental health scores. The hypothyroidism group displayed higher anxiety (p < 0.05) and better memory (p < 0.05), while the diabetic group exhibited higher depression (p < 0.05). Results showed a higher prevalence of severe anxiety and depression in the diabetic group compared to the hypothyroidism group. Notably, the diabetic group also showed a significantly higher proportion of participants with moderate memory problems.

Conclusions

This study suggests that both hypothyroidism and type-2 diabetes mellitus can impact mental health in middle-aged women. Type-2 diabetes mellitus appears to be associated with a greater prevalence of severe category of anxiety and depression, and with greater individuals in the moderate memory level category. These findings highlight the importance of comprehensive assessments to identify and address mental health comorbidities in patients with these chronic conditions.
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中年妇女2型糖尿病和甲状腺功能减退的心理健康比较分析:一项横断面研究
甲状腺功能减退和2型糖尿病等非传染性疾病正变得越来越普遍,并可能导致焦虑、抑郁和记忆问题。尽管这些精神健康合并症严重影响生活质量,但往往未得到诊断。性别差异也被观察到,女性患这两种疾病的比例更高。目的:比较甲状腺功能减退和2型糖尿病中年妇女的焦虑、抑郁和记忆水平。方法采用横断面设计,从新德里Hakeem Abdul Hameed百年医院招募243名女性。参与者根据确诊的诊断分为甲状腺功能减退组和2型糖尿病组。使用问卷评估焦虑(GAD-7)、抑郁(PHQ-9)和记忆(PGI-memory)。数据分析采用独立样本t检验和卡方检验。结果差异有统计学意义(p <;平均心理健康得分出现0.05)。甲状腺功能减退组表现出更高的焦虑(p <;0.05)和更好的记忆力(p <;0.05),而糖尿病组抑郁程度更高(p <;0.05)。结果显示,与甲状腺功能减退组相比,糖尿病组中严重焦虑和抑郁的患病率更高。值得注意的是,糖尿病组有中度记忆问题的参与者比例也明显更高。结论甲状腺功能减退和2型糖尿病均可影响中年妇女的心理健康。2型糖尿病似乎与更普遍的严重类型的焦虑和抑郁相关,并且与更多的中等记忆水平类别的个体相关。这些发现强调了综合评估的重要性,以确定和解决这些慢性疾病患者的精神健康合并症。
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来源期刊
Clinical Epidemiology and Global Health
Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
4.60
自引率
7.70%
发文量
218
审稿时长
66 days
期刊介绍: Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.
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