Nanoformulations of bioactive compounds derived from essential oils with antimicrobial activity

Valentina Nieto Marín , Danieli Fernanda Buccini , Viviane Gomes da Silva , Ian Alejandro Fernandez Soliz , Octávio Luiz Franco
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Abstract

Nanomaterial-based platforms for the formulation of bioactive compounds derived from essential oils (dEOs) have attracted considerable attention due to their potential to enhance the stability, controlled release, and antimicrobial efficacy of these natural compounds. This review analyzes the various nanomaterial platforms used for dEOs, including polymeric nanoparticles, liposomes, cyclodextrin and chitosan complexes, and inorganic nanosystems. The synthesis methods, physicochemical properties, and characterization techniques associated with these nanomaterial platforms are reviewed to elucidate their impact on the formulation and stability of dEOs. Furthermore, the antimicrobial activity of dEO formulations against a wide range of pathogenic microorganisms is described, highlighting the potential applications of these platforms in the treatment of infections and food preservation. The review also discusses the current challenges and prospects in the field, aiming to provide valuable insights for researchers and industry professionals involved in the development of nanomaterial-based dEO delivery systems.

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从具有抗菌活性的精油中提取的生物活性化合物的纳米配方
基于纳米材料的精油生物活性化合物制备平台因其具有增强天然化合物稳定性、控释和抗菌功效的潜力而受到广泛关注。本文综述了各种用于dEOs的纳米材料平台,包括聚合物纳米粒子、脂质体、环糊精和壳聚糖配合物以及无机纳米系统。本文综述了与这些纳米材料平台相关的合成方法、物理化学性质和表征技术,以阐明它们对dEOs的配方和稳定性的影响。此外,本文还描述了dEO制剂对多种病原微生物的抗菌活性,强调了这些平台在治疗感染和食品保存方面的潜在应用。本文还讨论了该领域目前面临的挑战和前景,旨在为研究人员和行业专业人士提供有价值的见解,以开发基于纳米材料的dEO输送系统。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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