Intérêt de la surveillance des pneumocoques dans le microbiote rhinopharyngé

Q4 Medicine Journal de Pediatrie et de Puericulture Pub Date : 2024-12-01 Epub Date: 2024-12-19 DOI:10.1016/S0987-7983(24)00153-1

R. Cohen , C. Levy , N. Ouldali , S. Bonacorsi , E. Varon

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Abstract

The nasopharyngeal microbiota represents a complex ecosystem made up of several hundred bacterial species, f ve of which are frequently associated with paediatric infections: Streptococcus pneumoniae (Sp), Haemophilus influenzas (Hi), Moraxelle catarrhalis (Mc), Streptococcus pyogenes and Staphylococcus aureus (SA), and will be discussed here.

The introduction of pneumococcal conjugate vaccines, however, represented a veritable ecological revolution in the respiratory tract microbiota, altering the carriage of pneumococci, causing vaccine serotypes to be replaced by other, less pathogenic serotypes, and reducing both invasive and non-invasive infections.

The impact of vaccination programs with conjugate vaccines, carriage in healthy children and in children with acute otitis media are reported here through a study of over 20,000 children over the past 25 years.

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监测鼻咽微生物中肺炎球菌的重要性

鼻咽部微生物群是一个由数百种细菌组成的复杂生态系统，其中五种细菌经常与儿科感染有关：肺炎链球菌（Sp）、流感嗜血杆菌（Hi）、卡他莫拉菌（Mc）、化脓性链球菌和金黄色葡萄球菌（SA），这里将进行讨论。然而，肺炎球菌结合疫苗的引入代表了呼吸道微生物群中真正的生态革命，改变了肺炎球菌的携带，导致疫苗血清型被其他致病性较低的血清型所取代，并减少了侵入性和非侵入性感染。结合疫苗接种计划的影响，健康儿童和急性中耳炎儿童的携带，通过过去25年对2万多名儿童的研究报告。©2024作者。Elsevier Masson SAS出版。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal de Pediatrie et de Puericulture Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.10

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0.00%

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期刊介绍： Les articles du Journal de pédiatrie et de puériculture traitent en profondeur tous les aspects des soins à enfant dont la diversité est à image de ces professions aux rôles multiples. Les sujets traités couvrent le traitement et les soins aux enfants malades, le conseil génétique, ainsi que les techniques de pointe : nouvelles approches du diagnostic prénatal, génie génétique, etc. Les disciplines concernées sont nombreuses : pédiatrie générale, médecine fœtale et néonatale, nutrition, dermatologie, pharmacologie, psychiatrie et psychologie, puériculture pratique, enfant et société, nouvelles des congrès.