Bringing lab to the field: Exploring innovations in point-of-care diagnostics for the rapid detection and management of tropical diseases in resource-limited settings

Abdullahi Tunde Aborode , Ridwan Olamilekan Adesola , Godfred Yawson Scott , Emele Arthur-Hayford , Oche Joseph Otorkpa , Somuah Daniel Kwaku , Emmanuel Ebuka Elebesunu , Eghaghe Osadebamwen Nibokun , Ibude Jane Aruorivwooghene , Adetolase A. Bakre , Oluwaseun Adeolu Ogundijo , Olamilekan Gabriel Banwo , Oluwatobiloba Ige , Ibrahim O. Adelakun , Isreal Ayobami Onifade , Segun E. Ogungbemi , Boluwatife T. Dosunmu , Oluwaseunayo Deborah Ayando , Nike Idowu , Grace A. Adegoye , Olusegun Oluwaseun Jimoh
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Abstract

Tropical diseases present major health challenges in regions with limited resources, where access to advanced laboratory facilities is often scarce. This study explores the innovative techniques emerging in point-of-care (POC) diagnostics that are transforming the detection and treatment of tropical diseases. These advancements aim to provide faster diagnosis, better medical care, and ongoing monitoring in areas where traditional diagnostic methods are not practical, combining the precision of laboratory testing with the accessibility of field-based solutions. The review focuses on rapid diagnostic tests, molecular diagnostic tools, and smartphone-based applications, analyzing their advantages, limitations, and potential impact on healthcare delivery. It also addresses the challenges and opportunities involved in deploying these technologies in resource-constrained environments. Key to their success is the need for interdisciplinary collaboration, sustainable funding models, and strong regulatory frameworks to ensure their effective integration into healthcare systems. The review emphasizes how point-of-care diagnostics can play a crucial role in reducing the burden of tropical diseases and advancing health equity on a global scale.
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将实验室带到实地:探索在资源有限的环境中快速检测和管理热带病的即时诊断创新
在资源有限的地区,热带病是重大的卫生挑战,在这些地区,获得先进实验室设施的机会往往很少。本研究探讨了正在改变热带病检测和治疗的即时诊断(POC)中出现的创新技术。这些进步的目的是在传统诊断方法不实用的领域提供更快的诊断、更好的医疗护理和持续监测,将实验室检测的精确性与实地解决方案的可及性相结合。这篇综述的重点是快速诊断测试、分子诊断工具和基于智能手机的应用,分析了它们的优势、局限性和对医疗保健服务的潜在影响。它还解决了在资源受限的环境中部署这些技术所涉及的挑战和机遇。它们成功的关键是需要跨学科合作、可持续的筹资模式和强有力的监管框架,以确保它们有效地融入卫生保健系统。该审查强调了即时诊断如何能够在全球范围内减轻热带病负担和促进卫生公平方面发挥关键作用。
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来源期刊
Advances in biomarker sciences and technology
Advances in biomarker sciences and technology Biotechnology, Clinical Biochemistry, Molecular Medicine, Public Health and Health Policy
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审稿时长
20 weeks
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