Bioreactor Engineering for Circular Economy: Bioactive Compound Production in Solid-State Fermentation—Review

IF 1.8 4区工程技术 Q3 ENGINEERING, CHEMICAL Chemical Engineering & Technology Pub Date : 2024-11-14 DOI:10.1002/ceat.202400289

Dr. Gerardo A. Gómez-Ramos, Dr. Lilia A. Prado-Barragán, Brianda A. Rivera, Dr. Sergio Huerta-Ochoa, Dr. Víctor M. Rivera, Dr. Moises Couder-García, Dr. Rocío de los Ángeles García-Hernández, Dr. Carlos O. Castillo-Araiza

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Abstract

Solid-state fermentation (SSF) has gained considerable attention due to its potential in the production of bioactive compounds from agroindustrial residues, aligning with circular economy targets. This review examines the core bases involved in SSF with a focus on bioreactor engineering. The review underlines the microorganisms metabolic activities under different operational conditions and focuses on engineering challenges encountered in designing packed-bed bioreactors, including an analysis of the interaction between microbial growth kinetics and transport phenomena. Finally, given its essential role in the scaling-up process, this review discusses mathematical modeling developed for SSF in packed-bed bioreactors, establishing a foundation for the future development of more efficient, scalable, and sustainable SSF-based applications.

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来源期刊

Chemical Engineering & Technology 工程技术-工程：化工

CiteScore

3.80

自引率

4.80%

发文量

315

审稿时长

5.5 months

期刊介绍： This is the journal for chemical engineers looking for first-hand information in all areas of chemical and process engineering. Chemical Engineering & Technology is: Competent with contributions written and refereed by outstanding professionals from around the world. Essential because it is an international forum for the exchange of ideas and experiences. Topical because its articles treat the very latest developments in the field.

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