{"title":"Biosensors responsive to glucose uptake rates can dynamically regulate metabolic flux","authors":"","doi":"10.1038/s44286-025-00174-1","DOIUrl":null,"url":null,"abstract":"When glucose is used as the main carbon source in microbial cultures, its uptake rate directly influences the overall metabolic flux. This study presents genetic circuits that can detect the glucose uptake rate and dynamically regulate the associated metabolic fluxes and the synthesis of desired products.","PeriodicalId":501699,"journal":{"name":"Nature Chemical Engineering","volume":"2 1","pages":"34-35"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Chemical Engineering","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44286-025-00174-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
When glucose is used as the main carbon source in microbial cultures, its uptake rate directly influences the overall metabolic flux. This study presents genetic circuits that can detect the glucose uptake rate and dynamically regulate the associated metabolic fluxes and the synthesis of desired products.
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