18F-FDG PET/CT findings of erythema induratum

Q4 Medicine Radiology Case Reports Pub Date : 2025-04-01 Epub Date: 2025-02-04 DOI:10.1016/j.radcr.2025.01.067
KyungAh Chun MD, PhD
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Abstract

18F-FDG (fluorodeoxyglucose) accumulates in malignant tissues but also at the sites of infection and inflammation and in autoimmune and granulomatous diseases by the overexpression of distinct facultative glucose transporter (GLUT) isotypes (mainly GLUT-1 and GLUT-3) in cancer cells and inflammatory cells.
A 75-year-old female with a history of skin rash with tenderness for 1 month underwent 18F-FDG positron emission tomography/computed tomography (PET/CT) to determine the presence of an underlying disease including malignant tumor. The 18F-FDG PET/CT showed hypermetabolic nodules at subcutaneous tissue (right upper arm, bilateral lower back and buttock, both thigh). She was diagnosed with erythema induratum on biopsy.
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硬化性红斑的18F-FDG PET/CT表现
18F-FDG(氟脱氧葡萄糖)通过不同的兼性葡萄糖转运蛋白(GLUT)同种型(主要是GLUT-1和GLUT-3)在癌细胞和炎症细胞中的过度表达,在恶性组织中积累,但也在感染和炎症部位以及自身免疫和肉芽肿疾病中积累。一名75岁女性,因皮疹及压痛1个月,接受18F-FDG正电子发射断层扫描/计算机断层扫描(PET/CT)以确定是否存在包括恶性肿瘤在内的潜在疾病。18F-FDG PET/CT显示皮下组织(右上臂,双侧下背部和臀部,双大腿)高代谢结节。活检诊断为硬皮肿。
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来源期刊
Radiology Case Reports
Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
1.10
自引率
0.00%
发文量
1074
审稿时长
30 days
期刊介绍: The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.
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