Pilocytic astrocytoma: A rare case report

Q4 Medicine Radiology Case Reports Pub Date : 2025-04-01 Epub Date: 2025-02-01 DOI:10.1016/j.radcr.2025.01.025
Harry Galuh Nugraha PhD , Elsa Yoasta MD , Mirna Sobana MD , Hermin Aminah Usman MD
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Abstract

Pilocytic astrocytoma (PA) is a rare, low-grade glioma predominantly affecting children and young adults, with a favorable prognosis and a high survival rate. Despite its’ slow growth, PA often presents with significant symptoms at diagnosis due to its tendency to reach a large size, especially in pediatric patients, where compensatory mechanisms can delay detection. This case report describes a 7-year-old girl with progressive vision loss, headache, and balance disturbance. The imaging result revealed a right cerebellar mass that was in accordance with pilocytic astrocytoma and obstructive hydrocephalus. Histopathologic analysis confirmed the diagnosis with the typical features of PA such as Rosenthal fibers and eosinophilic granular bodies. This case report highlights the critical role of radiologic and histopathologic evaluations for PA diagnosis and management; also the unique presentation and challenges in managing PA, emphasizing the importance of timely intervention to optimize neurological outcomes.
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毛细胞星形细胞瘤1例
毛细胞星形细胞瘤(PA)是一种罕见的低级别胶质瘤,主要影响儿童和年轻人,预后良好,生存率高。尽管PA生长缓慢,但在诊断时往往表现出明显的症状,因为它的体积往往很大,特别是在儿科患者中,代偿机制会延迟检测。这个病例报告描述了一个7岁的女孩进行性视力丧失,头痛和平衡障碍。影像结果显示右侧小脑肿块,符合毛细胞星形细胞瘤和阻塞性脑积水。组织病理学分析证实了PA的典型特征,如罗森塔尔纤维和嗜酸性颗粒体。本病例报告强调了放射学和组织病理学评估对PA诊断和治疗的关键作用;此外,在管理PA的独特表现和挑战,强调及时干预的重要性,以优化神经预后。
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来源期刊
Radiology Case Reports
Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
1.10
自引率
0.00%
发文量
1074
审稿时长
30 days
期刊介绍: The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.
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