Bohai Li , Longxiang Ye , Yongfu Chen , Heping Zhang
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引用次数: 0
Abstract
Probiotics have emerged as a promising approach to modulate gut microbiota and their metabolic functions, particularly by facilitating the production of short-chain fatty acids, bile acids, and indoles. However, detailed insights into the specific genes, enzymes, and biochemical pathways involved are limited. This review elucidates current knowledge on how probiotics and gut microorganisms metabolize dietary carbohydrates, proteins, and fats into bioactive metabolites from a genomic perspective. Additionally, the potential of genetic strategies to enhance the production of beneficial metabolites by probiotics is explored. By targeting and modifying specific genetic elements, it may be possible to optimize the therapeutic potential of probiotics. This review aims to deepen our understanding of underlying probiotic functions and offer new perspectives for developing bioengineered probiotics, paving the way for innovative therapeutic strategies for treating human diseases.
期刊介绍：
Current Opinion in Food Science specifically provides expert views on current advances in food science in a clear and readable format. It also evaluates the most noteworthy papers from original publications, annotated by experts.
Key Features:
Expert Views on Current Advances: Clear and readable insights from experts in the field regarding current advances in food science.
Evaluation of Noteworthy Papers: Annotated evaluations of the most interesting papers from the extensive array of original publications.
Themed Sections: The subject of food science is divided into themed sections, each reviewed once a year.
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