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Gaps and solutions for large scale production of cultured meat: a review on last findings
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-15 DOI: 10.1016/j.cofs.2024.101243
Da Young Lee, Sun Jin Hur
Despite initial expectations, the full-scale industrialization of cultured meat has not yet been realized owing to technical difficulties yet to be resolved. Therefore, this review discusses the delayed industrialization of cultured meat and strategies to overcome this delay. The identified challenges include a low cell growth rate, consistency, muscle satellite cell differentiation, completely defined medium components and their roles in myogenesis, effective fetal bovine serum replacement, and the inconsistencies of muscle formation in vitro. Another reason for the delay is the inherent dependence on animal-sourced cell culture products, which raise ethical concerns and are not considered safe for consumption. Technologies related to efficient cultured meat production remain imperative. This study also emphasizes the importance of using cell lines or immortalized cells and efficient culturing strategies to achieve the full industrialization of cultured meat.
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引用次数: 0
Editorial overview: Sensory science and consumer perception 2024
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-14 DOI: 10.1016/j.cofs.2024.101244
Matthew B McSweeney
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引用次数: 0
Quantitative tools in food safety and risk assessment to address technological innovations and climate change 应对技术创新和气候变化的食品安全和风险评估定量工具
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-12 DOI: 10.1016/j.cofs.2024.101237
Myrsini N Kakagianni , Enda Cummins , Vasilis P Valdramidis
In a globalized food market with an extensive agro-industrial sector, establishing and maintaining food safety is a significant challenge. Despite extensive research and advanced technological tools for monitoring and controlling food pathogens and toxins, outbreaks and toxification incidents persist. The complexity of food production, varied raw material sources, and differing governance levels highlight the need for a comprehensive approach to food safety. Climate change exacerbates the situation, as elevated temperatures may increase the likelihood of food pathogens or toxins reaching harmful levels. Understanding the multiple factors that undermine food safety, alongside advancements in monitoring and control strategies, including molecular (e.g. next-generation sequencing) and analytical (spectroscopic or chromatographic) technologies, can help address these challenges. Implementing a uniform comprehensive food safety platform can establish effective processes for estimating and ensuring food safety, helping to keep foodborne hazards at bay.
在农工部门广泛分布的全球化食品市场中,建立和维护食品安全是一项重大挑战。尽管在监测和控制食品病原体和毒素方面开展了广泛的研究,并采用了先进的技术手段,但疫情爆发和毒素中毒事件仍屡禁不止。食品生产的复杂性、原材料来源的多样性以及不同的管理水平,都凸显了对食品安全采取综合方法的必要性。气候变化使情况更加恶化,因为温度升高可能会增加食品病原体或毒素达到有害水平的可能性。了解破坏食品安全的多种因素,同时采用先进的监测和控制策略,包括分子(如下一代测序)和分析(光谱或色谱)技术,有助于应对这些挑战。实施统一的综合性食品安全平台,可以建立有效的食品安全评估和确保流程,帮助遏制食源性危害。
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引用次数: 0
Precision fermentation for producing food ingredients
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-12 DOI: 10.1016/j.cofs.2024.101242
Sumin Cho , Seok Yeong Jung , Hyunmin Eun , Sang Yup Lee
Fermentation has been crucial in human history, evolving in meaning with advances in biotechnology. Advancements in synthetic biology and metabolic engineering have led to the emergence of precision fermentation, which involves using metabolically engineered microbes to produce functional ingredients from simple carbon sources under precisely controlled conditions. These technologies have the potential to develop sustainable platforms for producing food ingredients, which could help address food crisis issues. This review discusses how systems metabolic engineering can be applied to precision fermentation-based production of food ingredients in microbial hosts, with a particular focus on the production of flavoring and coloring agents. Additionally, the development of optimal downstream processing techniques for each product category is also examined.
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引用次数: 0
The volatile metabolome — gas chromatography–mass spectrometry approaches in the context of food fraud
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-08 DOI: 10.1016/j.cofs.2024.101235
Beatriz Quintanilla-Casas , Berta Torres-Cobos , Rasmus Bro , Francesc Guardiola , Stefania Vichi , Alba Tres
This work discusses food authentication tools based on the volatile metabolome assessed by gas chromatography-mass spectrometry (GC-MS). Volatile organic compounds (VOCs) serve as markers for food flavor and aroma, and in some cases, they hold potential for food authentication. On top of this, advanced data analysis approaches enhance analytical data extraction and understanding. Untargeted methods provide comprehensive authenticity insights, surpassing traditional targeted approaches, and automated processing improves robustness and reduces user dependency. Chemometric tools, particularly classification methods, are extensively used for authentication based on both GC-MS fingerprinting and untargeted profiling of VOCs. Despite challenges in transferability, untargeted methods perform well in authentication models, making them valuable for internal quality control and official control guidance for fraud detection. This work highlights the need for further research to establish untargeted authentication tools as official methods in the near future.
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引用次数: 0
Next-generation probiotics delivery: innovations and applications of single-cell encapsulation 新一代益生菌输送:单细胞封装的创新与应用
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-08 DOI: 10.1016/j.cofs.2024.101234
Aijun Xie, Mengge Gao, Haishun Du, Xuejun Pan
Probiotics have demonstrated significant health benefits, particularly in gastrointestinal health, but their viability is often compromised by environmental stress during production, storage, and transit through the digestive system. Traditional encapsulation techniques, such as spray drying and freeze-drying, have limitations in protecting probiotics. Recently, single-cell encapsulation has emerged as a promising strategy, providing individualized protection to each probiotic cell. This technique enhances stability, ensures targeted release in the gastrointestinal tract, and improves overall therapeutic effectiveness. This review explores the latest advancements in single-cell encapsulation, focusing on innovative wall materials, such as amino acids, Eudragit, and polyphenol complexes. Additionally, it discusses emerging applications in areas beyond gut health, including cancer therapy and bioimaging. Despite its potential, challenges remain in scaling production and ensuring efficacy in human trials. Addressing these issues could pave the way for next-generation probiotics with enhanced therapeutic capabilities.
益生菌对健康,尤其是胃肠道健康有显著的益处,但在生产、储存和消化系统转运过程中,它们的活力往往会受到环境压力的影响。喷雾干燥和冷冻干燥等传统封装技术在保护益生菌方面存在局限性。最近,单细胞封装技术成为一种很有前途的策略,它能为每个益生菌细胞提供个性化的保护。这种技术可提高稳定性,确保在胃肠道内定向释放,并提高整体治疗效果。本综述探讨了单细胞包被技术的最新进展,重点关注氨基酸、Eudragit 和多酚复合物等创新壁材。此外,它还讨论了肠道健康以外领域的新兴应用,包括癌症治疗和生物成像。尽管具有潜力,但在扩大生产规模和确保人体试验疗效方面仍存在挑战。解决这些问题可以为提高治疗能力的下一代益生菌铺平道路。
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引用次数: 0
Milk protein–polyphenol–saccharide ternary complexes: Improved health and functional properties 牛奶蛋白-多酚-多糖三元复合物:改善健康和功能特性
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-08 DOI: 10.1016/j.cofs.2024.101239
Lidong Pang , Runze Li , Zhen Huang , Xinyan Yang , Yujun Jiang
Milk protein–polyphenol–saccharide (MPPS) ternary complexes are receiving increasing attention for their superior health and functional properties. This paper systematically reviews recent advancements in MPPS for improving health and functional properties and discusses the remaining challenges and future trends. Research has proven that MPPS ternary complexes are a promising raw food material. However, the formation mechanism involved in MPPS and the mechanism through which the preparation conditions, the source of raw materials, and the order of preparation affect MPPS still need to be studied in-depth. Additionally, covalent preparation methods, casein-based MPPS, increased health and functional properties, and safety will require extensive in-depth research.
牛奶蛋白-多酚-多糖(MPPS)三元复合物因其卓越的健康和功能特性而受到越来越多的关注。本文系统回顾了 MPPS 在改善健康和功能特性方面的最新进展,并讨论了仍然存在的挑战和未来趋势。研究证明,MPPS 三元复合物是一种前景广阔的食品原料。然而,MPPS 的形成机理以及制备条件、原料来源和制备顺序对 MPPS 的影响机制仍有待深入研究。此外,共价制备方法、基于酪蛋白的 MPPS、更高的健康和功能特性以及安全性也需要广泛深入的研究。
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引用次数: 0
Next-generation probiotics: innovations in safety assessments 新一代益生菌:安全评估的创新
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-08 DOI: 10.1016/j.cofs.2024.101238
Ziyan Hua , Shu Liu , Guang Yang , Xiaoyue Hou , Yaowei Fang
The human gut microbiota is integral to health and disease, fostering the development of next-generation probiotics (NGPs) tailored for specific health conditions. This review addresses the safety assessments and development of NGPs, highlighting recent biotechnological advances that enable the customization of NGPs for specific health conditions. It examines the methodologies for in vitro and in vivo animal model assessments focusing on potential toxicity. Additionally, we explore the integration of multi-omics, synthetic biology, and advanced computational technologies, including artificial intelligence and machine learning, to enhance the precision and safety of NGPs. Incorporating NGPs into food matrices represents an effective approach to delivering these probiotics and enhancing the health benefits of food products. This review underscores the necessity of adopting comprehensive safety assessments to navigate the complexities of NGP development effectively.
人类肠道微生物群与健康和疾病密不可分,这促进了针对特定健康状况的下一代益生菌(NGPs)的开发。本综述探讨了 NGPs 的安全性评估和开发,重点介绍了近期生物技术的进步,这些进步使得针对特定健康状况定制 NGPs 成为可能。它探讨了体外和体内动物模型评估的方法,重点关注潜在的毒性。此外,我们还探讨了多组学、合成生物学和先进计算技术(包括人工智能和机器学习)的整合,以提高 NGPs 的精确性和安全性。将 NGPs 添加到食品基质中是提供这些益生菌并提高食品健康益处的有效方法。本综述强调了采用全面安全评估以有效驾驭复杂的 NGP 开发的必要性。
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引用次数: 0
Advances in smartphone-based biosensors for food testing 基于智能手机的食品检测生物传感器的进展
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-07 DOI: 10.1016/j.cofs.2024.101236
Shoucheng Qin, Xueyan Sun, Xihong Zhao
Food is an essential part of human life, and with economic growth, the focus has shifted from quantity to quality and safety. Rapid food testing, which involves identifying suspicious samples from a large number of food samples quickly, is crucial. A promising approach is to integrate current food analysis techniques with smartphone-based detection systems. This review summarizes recent developments in smartphone-based biosensors for portable food detection, presenting both single-mode and dual-mode biosensors on smartphones, as well as common materials used for optical sensing biosensors. The advancements in smartphone-based biosensors are driven by artificial intelligence technology. In this review, we discuss not only the technical principles and applications but also the challenges and future perspectives for smartphone-based biosensors.
食品是人类生活的重要组成部分,随着经济的增长,人们对食品的关注点已从数量转向质量和安全。快速食品检测,即从大量食品样本中快速识别可疑样本,至关重要。将当前的食品分析技术与基于智能手机的检测系统结合起来是一种很有前景的方法。本综述总结了基于智能手机的便携式食品检测生物传感器的最新发展,介绍了智能手机上的单模和双模生物传感器,以及光学传感生物传感器的常用材料。人工智能技术推动了基于智能手机的生物传感器的发展。在这篇综述中,我们不仅讨论了技术原理和应用,还讨论了基于智能手机的生物传感器所面临的挑战和未来前景。
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引用次数: 0
Elicitors: impact on the fungal pathogenicity and colonization in fruits 诱导剂:对水果中真菌致病性和定植的影响
IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-10-31 DOI: 10.1016/j.cofs.2024.101233
Cristina Hidalgo , Santiago Ruiz-Moyano , Manuel J Serradilla , Ana I Galván , Alicia Rodríguez
Fruit rotting caused by filamentous fungus is a serious global issue affecting both economics and food safety. Therefore, effective strategies to combat the occurrence of filamentous fungi in fruit are required. Elicitors, for example, have been demonstrated to improve the physicochemical, nutritional, and functional quality of fruits, making them desirable for controlling fungal colonization and mycotoxin production. In this review, we will first explore the problem of fungal colonization in fruits, as well as the primary control measures. Second, research into the effects of the most important elicitors on fruit quality has been conducted. Finally, the most current studies on elicitors’ influence on fungal growth, as well as their primary routes of action, are discussed. We can conclude that while there is evidence that elicitors can reduce fungal pathogenicity and mycotoxin formation, more in vivo research is needed to assess their efficacy in various fruit types and conditions.
丝状真菌引起的水果腐烂是一个严重的全球性问题,对经济和食品安全都有影响。因此,需要有效的策略来应对水果中丝状真菌的发生。例如,诱导剂已被证明能改善水果的理化、营养和功能质量,因此是控制真菌定殖和霉菌毒素产生的理想物质。在本综述中,我们将首先探讨水果中真菌定植的问题以及主要的控制措施。其次,研究最重要的激发剂对水果质量的影响。最后,我们将讨论目前关于诱导剂对真菌生长的影响及其主要作用途径的最新研究。我们可以得出这样的结论:虽然有证据表明激发剂可以减少真菌的致病性和霉菌毒素的形成,但还需要进行更多的体内研究,以评估它们在各种水果类型和条件下的功效。
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Current Opinion in Food Science
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