EVALUATION OF SEXUAL DYSFUNCTION AND ITS RELATIONSHIP WITH INFERTILITY IN POLYCYSTIC OVARY SYNDROME, A PRELIMINARY CROSS-SECTIONAL STUDY

Abstract

Objective

Polycystic Ovary Syndrome (PCOS) remains the most prevalent endocrine disorder affecting women of reproductive age,from adolescence through to menopause[1].PCOS can disrupt the normal functioning of the female reproductive system and adversely affect sexual health[2,3].The tendency to overlook non-fertility-related symptoms often leads to a delay in diagnosis and insufficient attention to enhancing overall women's well-being[4].It is crucial to evaluate the increased reproductive and health risks associated with PCOS. Assessing sexual and reproductive health challenges can lead to better management strategies for the syndrome[5].In this study, we aim to explore both the sexual function and infertility status of patients diagnosed with PCOS, particularly focusing on those who have not yet been diagnosed or informed about their condition.By evaluating these aspects prior to formal diagnosis, we can better understand the initial health status of these individuals and underscore the importance of integrated care in their treatment.

Materials and

Methods: For the diagnosis of PCOS, we applied the 2018 International Evidence-based Guideline, which enhances the earlier Rotterdam criteria from 2003[6]. Women of reproductive age who are sexually active were included in the study. While forming our patient group, those with infertility due to male factors or other female conditions and those with AMH levels inconsistent with their age were not included if they were suspected or confirmed to be part of this group.Our study group consisted of patients who had not previously been diagnosed with PCOS.Patients suspected of having PCOS underwent the FSFI survey to assess sexual function without being informed of the preliminary diagnosis,and a detailed medical history was recorded.

Results

According to the FSFI classification,16% of individuals(n=12)do not have sexual dysfunction,while 84%(n=65)do have sexual dysfunction. According to the FSFI classification, among individuals without sexual dysfunction, 58.3% (n=7) do not have infertility, while 41.7%(n=5) do. On the other hand, among individuals with sexual dysfunction,26.2%(n=17) do not have infertility, whereas 73.8%(n=48)do. A statistically significant difference in the presence of infertility was observed according to the FSFI classification(p=0.034).

Conclusion

Our study, which assesses the sexual functions of patients not previously diagnosed with PCOS and not informed of their diagnosis, is valuable in correlating sexual dysfunctions with infertility. There is a need for a separate evaluation of sexual dysfunctions in PCOS patients and consideration of sexual dysfunctions in infertility treatments. The approach to PCOS-related infertility should not only focus on metabolic causes but also potential sexual dysfunctions, with some patients potentially being treatable with sexual therapy and other similar interventions. Personalizing treatments is essential.