{"title":"Nanocarriers in skin cancer treatment: Emerging drug delivery approaches and innovations","authors":"Laxmi A. Jadhav, Satish K. Mandlik","doi":"10.1016/j.ntm.2024.100068","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Skin cancer is a growing global health issue, with rising incidence rates, particularly among Caucasian populations. It is the most common malignancy, contributing significantly to mortality and decreased quality of life worldwide. While surgical interventions remain the primary treatment, there is a pressing need for innovative strategies to reduce the morbidity and mortality associated with the disease. As the burden of skin cancer continues to grow, the medical community is increasingly exploring novel therapeutic approaches to improve patient outcomes.</div></div><div><h3>Main body</h3><div>Nanotechnology has introduced new possibilities for treating skin cancer, offering advantages in targeted drug delivery, advanced imaging, and diagnostics. Nanomaterials are especially useful in dermatology, as they enhance the penetration and retention of therapeutic agents while minimizing side effects. Various nanomaterials have been studied for their potential in treating skin disorders, including cancer. This review examines the role of nanotechnology in skin cancer treatment, focusing on the development and design of nanocarriers for the precise delivery of drugs. We also discuss the advantages of nanotechnology over traditional treatments, such as improved bioavailability and targeted action. Additionally, we explore clinical trials, patents and FDA approved products related to nanocarrier-based treatments for cancer and skin cancer, highlighting advancements in the field.</div></div><div><h3>Conclusion</h3><div>Nanotechnology holds significant promise in revolutionizing skin cancer treatment. As research progresses, it is expected that more effective, personalized therapies will emerge, ultimately improving patient outcomes. Integrating nanotechnology into clinical practice could elevate the standard of care, offering new hope in managing skin cancer.</div></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"4 ","pages":"Article 100068"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nano TransMed","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2790676024000396","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Skin cancer is a growing global health issue, with rising incidence rates, particularly among Caucasian populations. It is the most common malignancy, contributing significantly to mortality and decreased quality of life worldwide. While surgical interventions remain the primary treatment, there is a pressing need for innovative strategies to reduce the morbidity and mortality associated with the disease. As the burden of skin cancer continues to grow, the medical community is increasingly exploring novel therapeutic approaches to improve patient outcomes.
Main body
Nanotechnology has introduced new possibilities for treating skin cancer, offering advantages in targeted drug delivery, advanced imaging, and diagnostics. Nanomaterials are especially useful in dermatology, as they enhance the penetration and retention of therapeutic agents while minimizing side effects. Various nanomaterials have been studied for their potential in treating skin disorders, including cancer. This review examines the role of nanotechnology in skin cancer treatment, focusing on the development and design of nanocarriers for the precise delivery of drugs. We also discuss the advantages of nanotechnology over traditional treatments, such as improved bioavailability and targeted action. Additionally, we explore clinical trials, patents and FDA approved products related to nanocarrier-based treatments for cancer and skin cancer, highlighting advancements in the field.
Conclusion
Nanotechnology holds significant promise in revolutionizing skin cancer treatment. As research progresses, it is expected that more effective, personalized therapies will emerge, ultimately improving patient outcomes. Integrating nanotechnology into clinical practice could elevate the standard of care, offering new hope in managing skin cancer.