Brain network modulation in response to directional and Non-Directional Cues: Insights from EEG connectivity and graph theory

IF 3.7 3区医学 Q1 CLINICAL NEUROLOGY Clinical Neurophysiology Pub Date : 2025-01-24 DOI:10.1016/j.clinph.2025.01.007

Fabrizio Vecchio , Francesca Miraglia , Chiara Pappalettera , Paolo Maria Rossini

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引用次数: 0

Abstract

Objective

Directional cues have a profound impact on cognitive processes and behavior, and studying the involved brain networks can provide insights into their processing. This research aimed to investigate the neural network modulation associated with cognitive processing after the administration of directional cues using connectivity and graph theory.

Methods

Twenty healthy volunteers were enrolled and underwent EEG recording while they were asked to perform a visuomotor task, such as directional (DS) and non-directional (nDS). From EEG data, network parameters such as Small-World (SW) and Lagged linear connectivity across different EEG frequency bands were evaluated, analyzing the response to DS and nDS.

Results

The results revealed significant differences in the SW index, particularly in the Alpha 1 band, where participants exhibited a higher SW index when presented with DS compared to nDS. Moreover, the analysis of Alpha 1 band Lagged linear connectivity revealed close to statistically significant differences predominantly in the frontal and central regions.

Conclusions

This research contributes to our understanding of the neural mechanisms underlying the processing of directional cues.

Significance

It has potential implications for rehabilitation settings, for example in the rehabilitation of visual dysfunction and motor impairment following a stroke, by optimizing cognitive processing to enhance functional outcomes.

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来源期刊

Clinical Neurophysiology 医学-临床神经学

CiteScore

8.70

自引率

6.40%

发文量

932

审稿时长

59 days

期刊介绍： As of January 1999, The journal Electroencephalography and Clinical Neurophysiology, and its two sections Electromyography and Motor Control and Evoked Potentials have amalgamated to become this journal - Clinical Neurophysiology. Clinical Neurophysiology is the official journal of the International Federation of Clinical Neurophysiology, the Brazilian Society of Clinical Neurophysiology, the Czech Society of Clinical Neurophysiology, the Italian Clinical Neurophysiology Society and the International Society of Intraoperative Neurophysiology.The journal is dedicated to fostering research and disseminating information on all aspects of both normal and abnormal functioning of the nervous system. The key aim of the publication is to disseminate scholarly reports on the pathophysiology underlying diseases of the central and peripheral nervous system of human patients. Clinical trials that use neurophysiological measures to document change are encouraged, as are manuscripts reporting data on integrated neuroimaging of central nervous function including, but not limited to, functional MRI, MEG, EEG, PET and other neuroimaging modalities.