Thi Minh Chau Ngo , Dong Duong Ton That , Phuong Anh Ton Nu , Le Chi Cao , My Nguyen Thi Tra , Thi Quynh Trang Tran
{"title":"A case report of childhood onychomycosis caused by the rare yeast Kodamaea ohmeri","authors":"Thi Minh Chau Ngo , Dong Duong Ton That , Phuong Anh Ton Nu , Le Chi Cao , My Nguyen Thi Tra , Thi Quynh Trang Tran","doi":"10.1016/j.mmcr.2025.100695","DOIUrl":null,"url":null,"abstract":"<div><div>Onychomycosis is an uncommon disease in pediatric patients with dermatophytes and <em>Candida</em> spp. being the main causative agents. <em>Kodamaea ohmeri</em> has recently emerged as a human pathogen, including an onychomycosis causative agent. Here, we report the first case of childhood onychomycosis caused by <em>K. ohmeri</em> in Vietnam, presenting clinically as a white superficial onychomycosis. Fungal identification was confirmed by sequencing of the ITS1-2 region. Antifungal susceptibility testing revealed low minimum inhibitory concentrations for all tested agents, except fluconazole and caspofungin. The patient was treated with 2 % ketoconazole cream one month, resulting in complete resolution of the nail damage with no relapse observed after six months.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100695"},"PeriodicalIF":1.3000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753925000041","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/20 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Onychomycosis is an uncommon disease in pediatric patients with dermatophytes and Candida spp. being the main causative agents. Kodamaea ohmeri has recently emerged as a human pathogen, including an onychomycosis causative agent. Here, we report the first case of childhood onychomycosis caused by K. ohmeri in Vietnam, presenting clinically as a white superficial onychomycosis. Fungal identification was confirmed by sequencing of the ITS1-2 region. Antifungal susceptibility testing revealed low minimum inhibitory concentrations for all tested agents, except fluconazole and caspofungin. The patient was treated with 2 % ketoconazole cream one month, resulting in complete resolution of the nail damage with no relapse observed after six months.
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