Iodine-catalyzed 1-Aryltriazene/CS2 duo for sonochemical synthesis of 3-Sulphenylindoles employing [BMIM(SO3H)][OTf] as recyclable promoting system.

Vinod Jadhav , Athmanand Anchi , Imamhusen Jamadar , Shruti S. Malunavar , Rajesh G. Kalkhambkar , Suraj M. Sutar
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Abstract

Iodine-catalyzed regioselective sulphenylation of various 3-substituted indoles using CS2 as potential tool is demonstrated. An efficient and eco-friendly protocol has been developed to synthesize libraries of 3-sulphenyl indoles by employing CS2 as sulphur coupling-linkage for various 1-aryltriaznes and indoles. Short reaction time, mild reaction conditions, recycle and reuse of ionic liquids (ILs) are the advantages of this methodology. A plausible reaction mechanism to narrate the exploitation of the catalytic and promoting systems is also highlights of this work.

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以[BMIM(SO3H)][OTf]为可循环促进体系,碘催化1-芳基三氮杂烯/CS2二偶体声化学合成3-亚砜。
以CS2为潜在工具,证明了碘催化各种3-取代吲哚的区域选择性磺化反应。利用CS2作为各种1-芳基三嗪和吲哚的硫偶联键,建立了一种高效、环保的合成3-亚苯基吲哚文库的方法。该方法具有反应时间短、反应条件温和、离子液体可回收再利用等优点。一个合理的反应机制来叙述催化和促进体系的开发也是本工作的亮点。
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