Sichen Zhang , Yu Fang , Jie Wang , Aobo Sun , Jiale Li , Xue Zhang , Chunfei Wang , Lutan Zhou , Lei Hu , Hui Wang
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引用次数: 0
Abstract
Lipid droplets (LDs), as an important organelle, play a crucial role in regulating cell metabolism and growth. When their function is disrupted, they may lead to a series of diseases, which makes the monitoring of LDs the focus of researchers. In this study, relying on the lipophilic properties of triphenylamine and using its derivatives as targeting groups, we developed a series of BODIPY-based fluorescent probes (X1-X5) based on NBO structure. Probes X1, X2, and X4 all exhibited good aggregation-induced emission (AIE) performance. In addition, these probes have excellent photostability and low cytotoxicity, and have a large stokes shift (>100 nm) in H2O. Especially, probe X4 has been successfully applied to living cell LDs imaging, providing valuable tools for the field of biological imaging.
期刊介绍：
JPPA publishes the results of fundamental studies on all aspects of chemical phenomena induced by interactions between light and molecules/matter of all kinds.
All systems capable of being described at the molecular or integrated multimolecular level are appropriate for the journal. This includes all molecular chemical species as well as biomolecular, supramolecular, polymer and other macromolecular systems, as well as solid state photochemistry. In addition, the journal publishes studies of semiconductor and other photoactive organic and inorganic materials, photocatalysis (organic, inorganic, supramolecular and superconductor).
The scope includes condensed and gas phase photochemistry, as well as synchrotron radiation chemistry. A broad range of processes and techniques in photochemistry are covered such as light induced energy, electron and proton transfer; nonlinear photochemical behavior; mechanistic investigation of photochemical reactions and identification of the products of photochemical reactions; quantum yield determinations and measurements of rate constants for primary and secondary photochemical processes; steady-state and time-resolved emission, ultrafast spectroscopic methods, single molecule spectroscopy, time resolved X-ray diffraction, luminescence microscopy, and scattering spectroscopy applied to photochemistry. Papers in emerging and applied areas such as luminescent sensors, electroluminescence, solar energy conversion, atmospheric photochemistry, environmental remediation, and related photocatalytic chemistry are also welcome.
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