Advancement in PMN-PT transparent piezoelectric ceramic for photoacoustic/ultrasound dual-mode imaging

IF 9.6 1区 材料科学 Q1 CHEMISTRY, PHYSICAL Journal of Materiomics Pub Date : 2025-07-01 Epub Date: 2024-08-30 DOI:10.1016/j.jmat.2024.100932
Pengkun Guo , Wen Gao , Riqiang Lin , Xiatian Wang , Jiale Lan , Jiaming Zhang , Yanan Wang , Lin Zhu , Yongcheng Zhang , Feng Li , Weijie Zheng , Tianlong Zhao , Kwok-Ho Lam , Xiaojing Gong , Zhihua Xie , Yalin Qin , Shujun Zhang
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Abstract

Dual-mode imaging combining photoacoustic and ultrasound modalities holds great promise for comprehensive tissue characterization. In traditional dual-mode imaging systems, however, the opaque ultrasound transducers are integrated in complex optical and ultrasound paths, leading to compromises in imaging efficiency and sensitivity. To address these challenges, we design and produce highly transparent Pb(Mg,Nb)O3PbTiO3 ceramics with exceptional transparency of 68%, alongside a remarkable ultrahigh piezoelectric d33 of 1500 pC/N. Leveraging this material, we fabricate a high-sensitivity transparent piezoelectric ultrasound transducer (TPUT) with a center frequency of 16 MHz and a bandwidth of 30%, which seamlessly integrating ultrasound and photoacoustic capabilities into one system to achieve simultaneous photoacoustic/ultrasound dual-mode imaging, showcasing a remarkable sensitivity for deep-tissue detection (e.g., 7.5 mm thick chicken breast meat). Additionally, in vivo photoacoustic imaging of subcutaneous microvasculature in a mouse ear was successfully achieved via 28 MHz TPUT. Our innovation not only advances imaging performance but also offers a cost-effective solution, paving the way for transformative biomedical imaging applications.

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用于光声/超声双模成像的PMN-PT透明压电陶瓷研究进展
结合光声和超声模式的双模成像对全面的组织表征具有很大的希望。然而,在传统的双模成像系统中,不透明超声换能器集成在复杂的光学和超声路径中,导致成像效率和灵敏度降低。为了应对这些挑战,我们设计并生产了高透明度的Pb(Mg,Nb)O3PbTiO3陶瓷,其透明度高达68%,同时具有1500 pC/N的超高压电d33。利用这种材料,我们制造了一种高灵敏度透明压电超声换能器(TPUT),其中心频率为16 MHz,带宽为30%,将超声和光声能力无缝集成到一个系统中,实现同时光声/超声双模成像,显示出对深层组织检测(例如7.5 mm厚的鸡胸肉)的卓越灵敏度。此外,通过28 MHz TPUT成功地实现了小鼠耳内皮下微血管的体内光声成像。我们的创新不仅提高了成像性能,而且提供了具有成本效益的解决方案,为变革性生物医学成像应用铺平了道路。
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阿拉丁
Eu2O3
阿拉丁
TiO2
阿拉丁
PbO
阿拉丁
MgO
阿拉丁
Nb2O5
来源期刊
Journal of Materiomics
Journal of Materiomics Materials Science-Metals and Alloys
CiteScore
14.30
自引率
6.40%
发文量
331
审稿时长
37 days
期刊介绍: The Journal of Materiomics is a peer-reviewed open-access journal that aims to serve as a forum for the continuous dissemination of research within the field of materials science. It particularly emphasizes systematic studies on the relationships between composition, processing, structure, property, and performance of advanced materials. The journal is supported by the Chinese Ceramic Society and is indexed in SCIE and Scopus. It is commonly referred to as J Materiomics.
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