Individual variability in lactate response to cycling prescribed using physiological thresholds and peak work rate: a crossover within-participant repeated measures study.

IF 2.8 3区 医学 Q2 PHYSIOLOGY European Journal of Applied Physiology Pub Date : 2025-02-05 DOI:10.1007/s00421-025-05711-7
Lauren J Pacitti, Kaitlyn E Shikaze, Nia Simpson-Stairs, Jonathan Stringer, Brendon J Gurd
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引用次数: 0

Abstract

Purpose: (1) To determine if the blood lactate concentration ([BLa]) response is a repeatable individual trait, and (2) To examine whether threshold-based prescription (THR) reduces interindividual variability in [BLa] response compared to traditional (maximally anchored) exercise prescription (TRAD).

Method: A crossover within-participant repeated measures design was used to assess [BLa] during the TRAD and THR exercise in 17 participants (9 M/8F). Participants initially undertook an incremental test to exhaustion to determine peak work rate (WRpeak), a lactate threshold (LT) test and a critical power (CP) test. All baseline tests were repeated twice. Participants then completed 6 15-min bouts of continuous cycling at 65%WRpeak (TRAD; 3 bouts) and 80% of the difference (Δ80) between LT and CP (THR; 3 bouts). [BLa] response was measured at 10 and 15 min of exercise.

Results: Across individuals, there was a wide range in [BLa] response, but within individual responses were repeatable. [BLa] ranges and mean individual 90% confidence interval width (CIw) were as follows: TRAD@10 min = 2.1-9.7 mmol, CIw = 0.5 mmol, THR@10 min = 3.4-9.3 mmol, CIw = 0.6 mmol, TRAD@15 min = 2.2-9.9 mmol, CIw = 0.6 mmol, THR@15 min = 3.6-12.3 mmol, CIw = 0.7 mmol. Levene's tests revealed no significant differences in the variability of [BLa] response between TRAD and THR at 10 min (F = 0.523, p = 0.475) or 15 min (F = 0.351, p = 0.558) of exercise.

Conclusion: Our results demonstrate that true interindividual variability in the [BLa] response to exercise exists, but failed to confirm that variability in [BLa] response is reduced with the use of THR.

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来源期刊
CiteScore
6.00
自引率
6.70%
发文量
227
审稿时长
3 months
期刊介绍: The European Journal of Applied Physiology (EJAP) aims to promote mechanistic advances in human integrative and translational physiology. Physiology is viewed broadly, having overlapping context with related disciplines such as biomechanics, biochemistry, endocrinology, ergonomics, immunology, motor control, and nutrition. EJAP welcomes studies dealing with physical exercise, training and performance. Studies addressing physiological mechanisms are preferred over descriptive studies. Papers dealing with animal models or pathophysiological conditions are not excluded from consideration, but must be clearly relevant to human physiology.
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