Pub Date : 2026-01-12DOI: 10.1007/s00421-025-06103-7
Gustavo R Mota, Izabela A Santos, Anderson Luiz Rodrigues, Bernardo N Ide, Tom Citherlet, Jeffer E Sasaki, Moacir Marocolo
Purpose: We investigated whether an active protocol of ischemic preconditioning (IPC-A) would improve high-intensity intermittent exercise performance in youth team sport players.
Methods: Fifteen male amateur team sport players (15.5 ± 0.5 yrs) attended four different preconditioning sessions before the YoYo Intermittent Recovery Test level 1 (YYIR1) interspersed by seven days in a counterbalanced randomized cross-over design. IPC protocol consisted of three cycles of 5 min occlusion (220 mmHg) and 5 min reperfusion (0 mmHg) in both thighs. SHAM was similar to the IPC protocol, but 'occlusion' pressure was set up at 20 mmHg. Active protocols (IPC-A/ SHAM-A) were similar to the IPC/SHAM, but participants exercised (intermittent run) during the 'reperfusion' phases instead of resting. Six minutes after the protocol, the participants performed the YYIR1.
Results: The distance covered in the YYIR1 did not differ (p = 0.46) among the protocols: IPC (917 ± 204 m) vs. IPC-A (931 ± 211 m) vs. SHAM (968 ± 201 m) vs. SHAM-A (933 ± 204 m). Blood lactate concentration, and mean heart rate did not differ either (p > 0.05) among the protocols.
Conclusions: Active ischemic preconditioning involving exercise during reperfusion phase does not improve high-intensity intermittent exercise performance nor alter physiological or perceptual responses in youth team sport players.
目的:研究积极的缺血预处理方案(IPC-A)是否能改善青少年团队运动运动员的高强度间歇运动表现。方法:采用平衡随机交叉设计,15名男性业余团体运动员(15.5±0.5岁)在悠悠间歇恢复测试1级(YYIR1)前进行4次不同的预处理,每隔7天进行一次。IPC方案包括三个周期,分别为5分钟阻断(220 mmHg)和5分钟再灌注(0 mmHg)。SHAM与IPC方案相似,但“闭塞”压力设置为20mmhg。活动方案(IPC- a /SHAM - a)与IPC/SHAM相似,但参与者在“再灌注”阶段运动(间歇性跑步)而不是休息。6分钟后,参与者执行YYIR1。结果:YYIR1覆盖的距离在IPC(917±204 m) vs IPC- a(931±211 m) vs SHAM(968±201 m) vs SHAM- a(933±204 m)之间没有差异(p = 0.46)。不同治疗方案的血乳酸浓度和平均心率也无差异(p < 0.05)。结论:在再灌注阶段进行运动的主动缺血预处理不会改善高强度间歇运动的表现,也不会改变青少年团队运动运动员的生理或知觉反应。
{"title":"Ischemic preconditioning with active reperfusion does not improve high-intensity intermittent exercise in youth team sport players.","authors":"Gustavo R Mota, Izabela A Santos, Anderson Luiz Rodrigues, Bernardo N Ide, Tom Citherlet, Jeffer E Sasaki, Moacir Marocolo","doi":"10.1007/s00421-025-06103-7","DOIUrl":"https://doi.org/10.1007/s00421-025-06103-7","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated whether an active protocol of ischemic preconditioning (IPC-A) would improve high-intensity intermittent exercise performance in youth team sport players.</p><p><strong>Methods: </strong>Fifteen male amateur team sport players (15.5 ± 0.5 yrs) attended four different preconditioning sessions before the YoYo Intermittent Recovery Test level 1 (YYIR1) interspersed by seven days in a counterbalanced randomized cross-over design. IPC protocol consisted of three cycles of 5 min occlusion (220 mmHg) and 5 min reperfusion (0 mmHg) in both thighs. SHAM was similar to the IPC protocol, but 'occlusion' pressure was set up at 20 mmHg. Active protocols (IPC-A/ SHAM-A) were similar to the IPC/SHAM, but participants exercised (intermittent run) during the 'reperfusion' phases instead of resting. Six minutes after the protocol, the participants performed the YYIR1.</p><p><strong>Results: </strong>The distance covered in the YYIR1 did not differ (p = 0.46) among the protocols: IPC (917 ± 204 m) vs. IPC-A (931 ± 211 m) vs. SHAM (968 ± 201 m) vs. SHAM-A (933 ± 204 m). Blood lactate concentration, and mean heart rate did not differ either (p > 0.05) among the protocols.</p><p><strong>Conclusions: </strong>Active ischemic preconditioning involving exercise during reperfusion phase does not improve high-intensity intermittent exercise performance nor alter physiological or perceptual responses in youth team sport players.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-06DOI: 10.1007/s00421-025-06116-2
Arturo Ladriñán-Maestro, Jorge Sánchez-Infante, David Rodríguez-Sanz, Alberto Sánchez-Sierra
Purpose: This randomized controlled clinical trial aimed to assess the short-term effects of inspiratory muscle fatigue and warm-up on respiratory muscle strength and diaphragm thickness in professional basketball players.
Methods: Thirty-eight professional basketball players randomly allocated into an Inspiratory Muscle Fatigue group (FG) or an Inspiratory Muscle Warm-up group (WG). Diaphragmatic ultrasound parameters (inspiratory thickness, thickening fraction) and maximal inspiratory pressure (MIP), measured at baseline, immediately post-intervention, and at 15 and 30 min post-intervention.
Results: Compared with baseline, the FG showed decreases of 7% in MIP, 11% in inspiratory diaphragm thickness, and 26% in thickening fraction (all p < 0.01; η² = 0.38-0.68). In contrast, the WG demonstrated increases of 5% in MIP, 9% in inspiratory thickness, and 17% in thickening fraction immediately and 15 min after the intervention (p < 0.01). All outcomes showed strong group × time interactions (η² ≥ 0.74). Improvements in the WG diminished by 30 min.
Conclusions: Inspiratory muscle fatigue induces short-term impairments in inspiratory muscle strength and diaphragm thickness lasting at least 30 min. In contrast, inspiratory muscle warm-up elicits transient improvements lasting up to 15 min.
Trial registration: This trial was prospectively registered at ClinicalTrials.gov (NCT07046637) on July 10, 2025.
{"title":"Short-term effects of inspiratory muscle warm-up and fatigue on diaphragmatic function in professional basketball players: a randomized clinical trial.","authors":"Arturo Ladriñán-Maestro, Jorge Sánchez-Infante, David Rodríguez-Sanz, Alberto Sánchez-Sierra","doi":"10.1007/s00421-025-06116-2","DOIUrl":"https://doi.org/10.1007/s00421-025-06116-2","url":null,"abstract":"<p><strong>Purpose: </strong>This randomized controlled clinical trial aimed to assess the short-term effects of inspiratory muscle fatigue and warm-up on respiratory muscle strength and diaphragm thickness in professional basketball players.</p><p><strong>Methods: </strong>Thirty-eight professional basketball players randomly allocated into an Inspiratory Muscle Fatigue group (FG) or an Inspiratory Muscle Warm-up group (WG). Diaphragmatic ultrasound parameters (inspiratory thickness, thickening fraction) and maximal inspiratory pressure (MIP), measured at baseline, immediately post-intervention, and at 15 and 30 min post-intervention.</p><p><strong>Results: </strong>Compared with baseline, the FG showed decreases of 7% in MIP, 11% in inspiratory diaphragm thickness, and 26% in thickening fraction (all p < 0.01; η² = 0.38-0.68). In contrast, the WG demonstrated increases of 5% in MIP, 9% in inspiratory thickness, and 17% in thickening fraction immediately and 15 min after the intervention (p < 0.01). All outcomes showed strong group × time interactions (η² ≥ 0.74). Improvements in the WG diminished by 30 min.</p><p><strong>Conclusions: </strong>Inspiratory muscle fatigue induces short-term impairments in inspiratory muscle strength and diaphragm thickness lasting at least 30 min. In contrast, inspiratory muscle warm-up elicits transient improvements lasting up to 15 min.</p><p><strong>Trial registration: </strong>This trial was prospectively registered at ClinicalTrials.gov (NCT07046637) on July 10, 2025.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-06DOI: 10.1007/s00421-025-06063-y
Xiaoyang Pan, Kim Geok Soh, Wan Marzuki Wan Jaafar, He Sun
Purpose: Skill testing is a key component of sports science, yet research on golf performance assessment remains limited. This study aims to systematically review existing methods for evaluating golf performance and to visually present their design principles and indicator systems using a 3D bubble chart, ultimately proposing an optimized and standardized testing framework for golf skills.
Methods: Following the PRISMA guidelines, this study conducted a systematic search of Web of Science, PubMed, SPORTDiscus, Scopus, and Google Scholar, ultimately including 13 studies for analysis.
Results: Combined with 3D visualization indicate that existing research is overly concentrated on driving and putting, while iron and chipping tests are markedly underrepresented, limiting the comprehensive understanding of the four core golf skills. The number of shots and selection of measurement variables lack standardization. Although complex biomechanical and club-ball dynamics indicators can help explain performance mechanisms, overemphasis on these measures often overlooks the core objective of golf-getting the ball into the hole.
Conclusion: This study proposes a standardized modular testing framework centered on "target-hitting." Consists of four modules: ball-striking zone (e.g., grass, bunkers, slopes), target zone (e.g., fairway, green, and varying sizes), shot distance, and club selection. By adjusting the combination of modules, it can simulate complex scenarios and accommodate athletes of different skill levels, providing a scientific reference for research, training, and performance evaluation. This study also provides guidance on the test modules and test site setup.
目的:技术测试是运动科学的一个重要组成部分,然而对高尔夫表现评估的研究仍然有限。本研究旨在系统地回顾现有的高尔夫技术评估方法,并通过三维气泡图直观地呈现其设计原则和指标体系,最终提出一个优化的标准化的高尔夫技术测试框架。方法:本研究遵循PRISMA指南,系统检索Web of Science、PubMed、SPORTDiscus、Scopus、b谷歌Scholar,最终纳入13篇研究进行分析。结果:结合三维可视化显示,现有的研究过于集中在推杆和推杆测试上,而铁和削杆测试的代表性明显不足,限制了对高尔夫四项核心技术的全面理解。拍摄次数和测量变量的选择缺乏标准化。尽管复杂的生物力学和杆-球动力学指标可以帮助解释表现机制,但过分强调这些指标往往会忽视高尔夫的核心目标——将球打入洞中。结论:本研究提出了一个以“击中目标”为中心的标准化模块化测试框架。由四个模块组成:击球区(如草地、沙坑、斜坡)、目标区(如球道、果岭和不同大小)、击球距离和球杆选择。通过调整模块组合,可以模拟复杂场景,适应不同技术水平的运动员,为研究、训练和成绩评估提供科学参考。本研究还提供了测试模块和测试场地设置的指导。
{"title":"Assessment of golf-specific skill performance: a systematic review, 3D visualization, and standardized testing framework.","authors":"Xiaoyang Pan, Kim Geok Soh, Wan Marzuki Wan Jaafar, He Sun","doi":"10.1007/s00421-025-06063-y","DOIUrl":"https://doi.org/10.1007/s00421-025-06063-y","url":null,"abstract":"<p><strong>Purpose: </strong>Skill testing is a key component of sports science, yet research on golf performance assessment remains limited. This study aims to systematically review existing methods for evaluating golf performance and to visually present their design principles and indicator systems using a 3D bubble chart, ultimately proposing an optimized and standardized testing framework for golf skills.</p><p><strong>Methods: </strong>Following the PRISMA guidelines, this study conducted a systematic search of Web of Science, PubMed, SPORTDiscus, Scopus, and Google Scholar, ultimately including 13 studies for analysis.</p><p><strong>Results: </strong>Combined with 3D visualization indicate that existing research is overly concentrated on driving and putting, while iron and chipping tests are markedly underrepresented, limiting the comprehensive understanding of the four core golf skills. The number of shots and selection of measurement variables lack standardization. Although complex biomechanical and club-ball dynamics indicators can help explain performance mechanisms, overemphasis on these measures often overlooks the core objective of golf-getting the ball into the hole.</p><p><strong>Conclusion: </strong>This study proposes a standardized modular testing framework centered on \"target-hitting.\" Consists of four modules: ball-striking zone (e.g., grass, bunkers, slopes), target zone (e.g., fairway, green, and varying sizes), shot distance, and club selection. By adjusting the combination of modules, it can simulate complex scenarios and accommodate athletes of different skill levels, providing a scientific reference for research, training, and performance evaluation. This study also provides guidance on the test modules and test site setup.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: This study investigates the effects of different levels of acute normobaric hypoxia on cognitive function and cerebral oxygenation in healthy young adults.
Methods: Twenty-four participants aged 18-30 years were exposed to hypoxia with an inspired oxygen fraction (FiO2) equivalent to 20.9%, 17.44%, 14.5% and 12.7%. They performed different cognitive tasks, including the Stroop test, Corsi blocks (forward and backward), the n-Back task (1-Back and 2-Back), and the Go/No-Go task. Cerebral oxygenation was measured using the near-infrared spectroscopy (NIRS) during each cognitive task.
Results: In this study, we did not observe any effect of hypoxia on cognitive performance. However, perceived difficulty increased with increasing hypoxia, especially for the Stroop task (p = 0.003, Kendall's W = 0.208) and Corsi (p = 0.018, Kendall's W = 0.152). NIRS results showed a progressive increase in deoxyhemoglobin (ΔHHb) and a progressive decrease in oxyhemoglobin (ΔO2Hb) with increasing hypoxia for all cognitive tasks. There was no effect on total hemoglobin (ΔtHb). Finally, positive correlations were found between pulse oxygen saturation (SpO2) and ΔTSI% and between SpO2 and ΔO2Hb for all tasks, while a negative correlation was observed between SpO2 and ΔHHb. No correlation was found between SpO2 or TSI% and cognitive performance.
Conclusion: In conclusion, cognitive function appears to be unaffected by acute exposure to acute normobaric hypoxia at FiO2 above 12.7%. These results suggest a complete compensation of oxygenation of the prefrontal cortex region in young healthy subjects.
{"title":"Cerebral oxygenation and cognitive performance under different acute normobaric hypoxic conditions: a fNIRS study.","authors":"Corentin Faucher, Aurélien Pichon, Nathan Mathe, Manuel Gimenes, Dimitri Theurot, Aurélien Maqua, Ayoub Boulares, Benoit Dugué, Olivier Dupuy","doi":"10.1007/s00421-025-06042-3","DOIUrl":"https://doi.org/10.1007/s00421-025-06042-3","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates the effects of different levels of acute normobaric hypoxia on cognitive function and cerebral oxygenation in healthy young adults.</p><p><strong>Methods: </strong>Twenty-four participants aged 18-30 years were exposed to hypoxia with an inspired oxygen fraction (FiO<sub>2</sub>) equivalent to 20.9%, 17.44%, 14.5% and 12.7%. They performed different cognitive tasks, including the Stroop test, Corsi blocks (forward and backward), the n-Back task (1-Back and 2-Back), and the Go/No-Go task. Cerebral oxygenation was measured using the near-infrared spectroscopy (NIRS) during each cognitive task.</p><p><strong>Results: </strong>In this study, we did not observe any effect of hypoxia on cognitive performance. However, perceived difficulty increased with increasing hypoxia, especially for the Stroop task (p = 0.003, Kendall's W = 0.208) and Corsi (p = 0.018, Kendall's W = 0.152). NIRS results showed a progressive increase in deoxyhemoglobin (ΔHHb) and a progressive decrease in oxyhemoglobin (ΔO<sub>2</sub>Hb) with increasing hypoxia for all cognitive tasks. There was no effect on total hemoglobin (ΔtHb). Finally, positive correlations were found between pulse oxygen saturation (SpO<sub>2</sub>) and ΔTSI% and between SpO<sub>2</sub> and ΔO<sub>2</sub>Hb for all tasks, while a negative correlation was observed between SpO<sub>2</sub> and ΔHHb. No correlation was found between SpO<sub>2</sub> or TSI% and cognitive performance.</p><p><strong>Conclusion: </strong>In conclusion, cognitive function appears to be unaffected by acute exposure to acute normobaric hypoxia at FiO<sub>2</sub> above 12.7%. These results suggest a complete compensation of oxygenation of the prefrontal cortex region in young healthy subjects.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-03DOI: 10.1007/s00421-025-06069-6
Eli Spencer Shannon, S Andy Sparks, Lars Robert McNaughton, Kelly Marrin, Craig Alan Bridge
{"title":"The effect of sodium bicarbonate mini-tablets in a carbohydrate hydrogel on prolonged high-intensity cycling performance and metabolism in acute normobaric hypoxia.","authors":"Eli Spencer Shannon, S Andy Sparks, Lars Robert McNaughton, Kelly Marrin, Craig Alan Bridge","doi":"10.1007/s00421-025-06069-6","DOIUrl":"https://doi.org/10.1007/s00421-025-06069-6","url":null,"abstract":"","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145892244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-03DOI: 10.1007/s00421-025-06115-3
Bruna T C Saraiva, William R Tebar, Debora T Furuta, Stefany C B Silva, Ewerton P Antunes, Guilherme Sousa, Gerson Ferrari, Luiz Carlos M Vanderlei, Diego Giulliano Destro Christofaro
{"title":"Association of meeting the 24-hour movement guidelines with heart rate variability in adults.","authors":"Bruna T C Saraiva, William R Tebar, Debora T Furuta, Stefany C B Silva, Ewerton P Antunes, Guilherme Sousa, Gerson Ferrari, Luiz Carlos M Vanderlei, Diego Giulliano Destro Christofaro","doi":"10.1007/s00421-025-06115-3","DOIUrl":"https://doi.org/10.1007/s00421-025-06115-3","url":null,"abstract":"","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145892241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-26DOI: 10.1007/s00421-025-06113-5
Wim G Groen
{"title":"The steep ramp test: an emerging allrounder for aerobic capacity assessment in health and disease.","authors":"Wim G Groen","doi":"10.1007/s00421-025-06113-5","DOIUrl":"https://doi.org/10.1007/s00421-025-06113-5","url":null,"abstract":"","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145833457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-24DOI: 10.1007/s00421-025-06109-1
Linn C Risvang, Jan-Willem van Dijk, Julia K Baumgart, Hannah M Rice, Anja M F Liljegren, Vegard Strøm, Truls Raastad, Kristin L Jonvik
{"title":"High prevalence of low bone mineral density in wheelchair users regardless of sports participation: a cross-sectional analysis of the bonewheel study.","authors":"Linn C Risvang, Jan-Willem van Dijk, Julia K Baumgart, Hannah M Rice, Anja M F Liljegren, Vegard Strøm, Truls Raastad, Kristin L Jonvik","doi":"10.1007/s00421-025-06109-1","DOIUrl":"https://doi.org/10.1007/s00421-025-06109-1","url":null,"abstract":"","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145818667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-24DOI: 10.1007/s00421-025-06100-w
M Morrone, T Hortobágyi, D Kidgell, J P Farthing, F Deriu, A Manca
The integration of Large Language Models (LLMs) into scientific writing presents significant opportunities for scholars but also risks, including misinformation and plagiarism. A new body of literature is shaping to verify the capability of LLMs to execute the complex tasks that are inherent to academic publishing. In this context this study was driven by the need to critically assess LLM's out-of-the-box performance in generating evidence synthesis reviews. To this end, the signature topic of the authors' group, cross-education of voluntary force, was chosen as a model. We prompted a popular LLM (Gemini 2.5 Pro, Deep Research enabled) to generate a scoping review on the neural mechanisms underpinning cross-education. The resulting unedited manuscript was submitted for formal peer-review to four leading subject-matter experts. Their qualitative feedback on manuscript's structure, content, and integrity was collated and analyzed. Peer-reviewers identified critical failures at fundamental stages of the review process. The LLM failed to: (1) identify specific research questions; (2) adhere to established methodological frameworks; (3) implement trustworthy search strategies; (4) objectively synthesize data. Importantly, the Results section was deemed interpretative rather than descriptive. Referencing was agreed as the worst issue being inaccurate, biased toward open-access sources (84%), and containing instances of plagiarism. The LLM also failed to hierarchize evidence, presenting minor or underexplored findings as established evidence. The LLM generated a non-systematic, poorly structured, and unreliable narrative review. These findings suggest that the selected LLM is incapable of autonomously performing scientific synthesis and requires massive human supervision to correct the observed issues.
将大型语言模型(llm)整合到科学写作中为学者提供了重要的机会,但也存在风险,包括错误信息和剽窃。一个新的文献体系正在形成,以验证法学硕士执行学术出版固有的复杂任务的能力。在这种背景下,这项研究是由需要批判性地评估法学硕士在生成证据合成评论方面的开箱即用的表现所驱动的。为此,笔者课题组的标志性课题“志愿力量的交叉教育”被选为样板。我们促使一个受欢迎的LLM (Gemini 2.5 Pro, Deep Research启用)生成一个关于支持交叉教育的神经机制的范围审查。由此产生的未经编辑的手稿被提交给四位主要的主题专家进行正式的同行评审。对他们对稿件结构、内容和完整性的定性反馈进行整理和分析。同行审稿人在评审过程的基本阶段确定了关键的失败。LLM未能:(1)确定具体的研究问题;(2)坚持既定的方法框架;(3)实施可信搜索策略;(4)客观地综合数据。重要的是,结果部分被认为是解释性的,而不是描述性的。参考文献被认为是最糟糕的问题,不准确,偏向于开放获取资源(84%),包含抄袭的例子。法学硕士也未能将证据分层,将次要或未充分探索的发现呈现为既定证据。法学硕士产生了一个非系统的,结构不良的,不可靠的叙述回顾。这些发现表明,所选择的法学硕士无法自主进行科学合成,需要大量的人工监督来纠正观察到的问题。
{"title":"Peer-reviewed by human experts: AI failed in key steps to generate a scoping review on the neural mechanisms of cross-education.","authors":"M Morrone, T Hortobágyi, D Kidgell, J P Farthing, F Deriu, A Manca","doi":"10.1007/s00421-025-06100-w","DOIUrl":"https://doi.org/10.1007/s00421-025-06100-w","url":null,"abstract":"<p><p>The integration of Large Language Models (LLMs) into scientific writing presents significant opportunities for scholars but also risks, including misinformation and plagiarism. A new body of literature is shaping to verify the capability of LLMs to execute the complex tasks that are inherent to academic publishing. In this context this study was driven by the need to critically assess LLM's out-of-the-box performance in generating evidence synthesis reviews. To this end, the signature topic of the authors' group, cross-education of voluntary force, was chosen as a model. We prompted a popular LLM (Gemini 2.5 Pro, Deep Research enabled) to generate a scoping review on the neural mechanisms underpinning cross-education. The resulting unedited manuscript was submitted for formal peer-review to four leading subject-matter experts. Their qualitative feedback on manuscript's structure, content, and integrity was collated and analyzed. Peer-reviewers identified critical failures at fundamental stages of the review process. The LLM failed to: (1) identify specific research questions; (2) adhere to established methodological frameworks; (3) implement trustworthy search strategies; (4) objectively synthesize data. Importantly, the Results section was deemed interpretative rather than descriptive. Referencing was agreed as the worst issue being inaccurate, biased toward open-access sources (84%), and containing instances of plagiarism. The LLM also failed to hierarchize evidence, presenting minor or underexplored findings as established evidence. The LLM generated a non-systematic, poorly structured, and unreliable narrative review. These findings suggest that the selected LLM is incapable of autonomously performing scientific synthesis and requires massive human supervision to correct the observed issues.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145818608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}