Is poor dietary quality in adolescence a risk factor for painful temporomandibular disorders and headaches in young adulthood? A prospective study in the Danish National Birth Cohort.

Abstract

Objective: To investigate the association between adolescents' dietary quality and the presence of painful temporomandibular disorder (p-TMD) and headaches in young adulthood.

Background: P-TMD is a common orofacial pain condition often associated with headaches and discomfort. Some studies have shown that dietary behaviors can impact chronic musculoskeletal pain. Although various factors such as sex, age, psychosocial aspects, and pain sensitivity contribute to p-TMD, the role of nutrition remains unclear.

Methods: The dietary quality of 32,247 singletons from the Danish National Birth Cohort (DNBC) at age 14 was assessed using the Healthy Eating Index (HEI) encompassing eight domains. Among these, 11,982 (37.1%) individuals completed the TMD pain screener and headache-related queries at age 18 and above. HEI and dietary domains were analyzed as potential risk factors for p-TMD and headaches.

Results: P-TMD was present in 3163 of the 11,982 members of the study population. HEI scores were divided into quartiles, with quartile four indicating the highest dietary quality. Quartile four showed a higher odds ratio (OR) for p-TMD than quartile one (OR = 1.14 [95% confidence interval (CI), 1.01-1.29]), but the significance was lost after adjustment for confounders (adjusted OR [aOR] = 1.12 [95% CI, 0.97-1.30]). Overall dietary quality was not significantly associated with headaches. However, specific dietary quality domains, such as dietary fibers (aOR = 0.97 [95% CI, 0.95-0.99]), fish (aOR = 0.98 [95% CI, 0.97-1.00]), sodium (aOR = 1.03 [95% CI, 1.01-1.06]), and added sugar (aOR = 0.97 [95% CI, 0.95-0.99]) were associated with headaches but not with p-TMD after adjustment.

Conclusion: Overall adolescent dietary quality did not significantly associate with p-TMD or headaches in young adulthood after adjusting for confounders. However, specific dietary domains exhibited weak but statistically significant associations with headaches. These findings underscore the interplay between diet and pain, calling for further research to unveil the underlying pathophysiological mechanisms connecting lifestyle, p-TMD, and headaches.