The scaffold protein RACK1 regulates root growth and gravitropic response by recruiting PINOID to phosphorylate the auxin efflux transporter PIN-FORMED2

IF 9.3 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Integrative Plant Biology Pub Date : 2025-02-06 DOI:10.1111/jipb.13858
Shujuan Zhang, Qi Liao, Jiale Li, Wenbao Liu, Xinwen Zhang, Xindi Tian, Shucai Wang, Qun Zhang
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Abstract

The scaffolding protein RACK1 is involved in polar auxin transport and signaling. It binds to PINOID and PIN-FORMED2, enhancing their interaction and phosphorylation-dependent auxin efflux. Knocking down RACK1 genes impairs auxin-related processes such as root growth and gravitropic response.

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支架蛋白RACK1通过募集PINOID磷酸化生长素外排转运蛋白pin - form2来调节根的生长和向地性反应。
支架蛋白RACK1参与极性生长素运输和信号传导。它结合PINOID和pin - formmed2,增强它们的相互作用和磷酸化依赖性生长素外排。敲低RACK1基因会损害生长素相关的过程,如根系生长和向地性反应。
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来源期刊
Journal of Integrative Plant Biology
Journal of Integrative Plant Biology 生物-生化与分子生物学
CiteScore
18.00
自引率
5.30%
发文量
220
审稿时长
3 months
期刊介绍: Journal of Integrative Plant Biology is a leading academic journal reporting on the latest discoveries in plant biology.Enjoy the latest news and developments in the field, understand new and improved methods and research tools, and explore basic biological questions through reproducible experimental design, using genetic, biochemical, cell and molecular biological methods, and statistical analyses.
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