Empirically Determining Binge/Purge Frequency Thresholds for Differentiating Anorexia Nervosa-Restricting Subtype vs. Binge–Purge Subtype

IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS International Journal of Eating Disorders Pub Date : 2025-02-06 DOI:10.1002/eat.24391
Sophie R. Abber, Devon Peterkin, Carina S. Brown, Thomas E. Joiner, Christina E. Wierenga, Lauren N. Forrest
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Abstract

Objective

While research supports differentiating anorexia nervosa into binge–purge (AN-BP) vs. restricting (AN-R) subtypes, DSM-5-TR does not provide a specific threshold of binge and/or purge episodes that constitutes an AN-BP vs. AN-R diagnosis. Our review of the literature suggests that cutoffs used for defining AN subtypes are rarely reported and, when reported, are highly heterogeneous. Inconsistent subtyping protocols limit generalizability and understanding of AN-R and AN-BP differences.

Method

The present study used structural equation modeling (SEM) trees to empirically determine the frequency of binge eating and/or purging that best differentiates AN subtypes. We then compared empirically determined groups on characteristics frequently found to differ between subtypes. Participants were 731 adolescents and adults with AN (94% female, Mage = 20, 72% clinically diagnosed with AN-R) in a partial hospitalization program who completed assessments of AN and comorbid symptoms at intake.

Results

SEM tree analyses yielded four subgroups: past-month binge/purge frequency 0 (AN-R; n = 396); frequency 1–3 (AN-BP1; n = 101); frequency 4–15 (AN-BP2; n = 130); and frequency > 16 (AN-BP3; n = 98). AN-R differed from higher frequency groups on 14/22 clinical characteristics, AN-BP1 differed from higher frequency groups on 11/22 clinical characteristics, and AN-BP2 differed from higher frequency groups on 2/22 clinical characteristics.

Conclusions

Findings suggest that one binge eating and/or purge episode in the past month provides adequate distinction between subtypes. These findings indicate that the DSM's definition of AN-BP may need to be revised to specify that the presence of any binge eating or purging, rather than “recurrent” binge eating or purging, is sufficient for subtyping AN.

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经验确定暴食/清除频率阈值以区分神经性厌食症限制亚型与暴食-清除亚型。
目的:虽然研究支持将神经性厌食症区分为暴食-清除(an - bp)和限制性(an - r)亚型,但DSM-5-TR并没有提供暴食和/或清除发作的特定阈值,以构成an - bp和an - r的诊断。我们对文献的回顾表明,用于定义AN亚型的截止值很少被报道,即使报道,也是高度异质的。不一致的亚型协议限制了AN-R和AN-BP差异的通用性和理解。方法:本研究使用结构方程模型(SEM)树来经验确定最能区分AN亚型的暴饮暴食和/或排便频率。然后,我们比较了经验确定组的特征,经常发现不同亚型之间存在差异。参与者是部分住院项目中患有AN的731名青少年和成人(94%为女性,Mage = 20, 72%临床诊断为AN- r),他们在入院时完成了AN和合并症的评估。结果:扫描电镜树分析产生了四个亚组:过去一个月暴食/清除频率0 (AN-R);n = 396);频率1-3 (AN-BP1;n = 101);频率4-15 (AN-BP2;n = 130);频率bbb16 (AN-BP3;n = 98)。AN-R与高频组在14/22临床特征上存在差异,AN-BP1与高频组在11/22临床特征上存在差异,AN-BP2与高频组在2/22临床特征上存在差异。结论:研究结果表明,过去一个月的一次暴食和/或排便发作足以区分亚型。这些发现表明,DSM对AN- bp的定义可能需要修改,以明确任何暴食或排便的存在,而不是“经常性”暴食或排便,都足以作为AN的亚型。
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来源期刊
CiteScore
10.00
自引率
12.70%
发文量
204
审稿时长
4-8 weeks
期刊介绍: Articles featured in the journal describe state-of-the-art scientific research on theory, methodology, etiology, clinical practice, and policy related to eating disorders, as well as contributions that facilitate scholarly critique and discussion of science and practice in the field. Theoretical and empirical work on obesity or healthy eating falls within the journal’s scope inasmuch as it facilitates the advancement of efforts to describe and understand, prevent, or treat eating disorders. IJED welcomes submissions from all regions of the world and representing all levels of inquiry (including basic science, clinical trials, implementation research, and dissemination studies), and across a full range of scientific methods, disciplines, and approaches.
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