Moving to lower-poverty neighborhoods offers broad benefits for children with asthma, regardless of sex or other baseline characteristics

Torie L. Grant MD, MHS , Laken C. Roberts Lavigne PhD, MPH , Craig Evan Pollack MD, MHS , Pete Cimbolic BA , Susan Balcer-Whaley MPH , Roger D. Peng PhD , Elizabeth C. Matsui MD, MHS , Corinne A. Keet MD, PhD
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Abstract

Background

It was previously found that moving to lower-poverty/higher-opportunity neighborhoods as part of a housing mobility program was associated with improvements in asthma exacerbations and symptoms among children with asthma. Whether some subsets of children with asthma experience a greater improvement in asthma morbidity after moving is unknown.

Objective

Our aim was to determine whether the benefits of moving to lower-poverty/higher-opportunity neighborhoods were concentrated in subsets of participants with asthma.

Methods

We conducted a secondary analysis of the participants in the Mobility Asthma Project. Generalized estimating equations were used to assess the association between moving and asthma exacerbations and maximum symptom days. Separately, these models were then stratified by sex, age, body mass index, allergic sensitization, asthma severity, and stress before the move to estimate stratum-specific odds ratios for moving.

Results

Participants broadly experienced a postmove reduction in odds of an exacerbation and maximum symptom days. Male children and children at a higher asthma controller medication treatment step experienced a greater reduction in maximum symptom days with moving.

Conclusion

Children with asthma experience a reduction in odds of an exacerbation and symptoms after moving to lower-poverty/higher-opportunity neighborhoods. These improvements in asthma outcomes are seen regardless of baseline sex, age, body mass index, allergic sensitization, asthma severity, and premove stress.
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无论性别或其他基线特征如何,搬到较低贫困的社区对哮喘儿童都有广泛的好处
之前的研究发现,作为住房流动计划的一部分,搬到低贫困/高机会的社区与哮喘患儿哮喘加重和症状的改善有关。是否某些哮喘儿童亚群在运动后哮喘发病率有更大的改善尚不清楚。我们的目的是确定迁移到低贫困/高机会社区的益处是否集中在哮喘患者的亚群中。方法对运动性哮喘项目的参与者进行二次分析。使用广义估计方程来评估运动与哮喘加重和最大症状天数之间的关系。另外,这些模型在移动前按性别、年龄、体重指数、过敏致敏性、哮喘严重程度和压力进行分层,以估计特定阶层的移动优势比。结果参与者普遍经历了术后恶化的几率和最大症状天数的减少。男性儿童和哮喘控制药物治疗步骤较高的儿童在运动时最大症状天数减少较多。结论:哮喘患儿搬到低贫困/高机会社区后,病情恶化和症状的几率降低。这些哮喘结果的改善与基线性别、年龄、体重指数、过敏致敏性、哮喘严重程度和术前应激无关。
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来源期刊
The journal of allergy and clinical immunology. Global
The journal of allergy and clinical immunology. Global Immunology, Allergology and Rheumatology
CiteScore
0.70
自引率
0.00%
发文量
0
审稿时长
92 days
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