Estado de malnutrición como factor pronóstico de eventos cardiovasculares adversos mayores (MACE) en los pacientes con fibrilación auricular

IF 0.9 Q4 PRIMARY HEALTH CARE Medicina de Familia-SEMERGEN Pub Date : 2025-02-07 DOI:10.1016/j.semerg.2025.102458

P. Moltó-Balado , J.L. Clua-Espuny , S. Reverté-Villarroya , M.T. Balado-Albiol , M. García-Olcina , A. Simeó-Monzó , A. Serra-Garcia , J. Canela-Royo

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Abstract

Objective

To examine nutritional status among patients with atrial fibrillation (AF) and its relationship with major adverse cardiovascular events (MACE), and to determine whether nutritional status is a risk factor for MACE in patients with AF.

Material and methods

Observational, retrospective, community-based study (n = 40,297) aged 65-95 years in Terres de l’Ebre (Catalonia, Spain) between 2015 and 2021. A total of 2,574 patients with a diagnosis of AF were included. The CONUT scale was used to assess nutritional status and Cox regression analyses were performed.

Results

67.91% of AF patients developed MACE. Malnutrition as assessed by the CONUT scale was significantly higher in AF patients who developed MACE (P < .001). Malnutrition doubled the risk of MACE and was identified as a prognostic factor (HR: 1.06; 95% CI: 1.04-1.08; P < .001).