Analysis of thiosemicarbazones as an effective spectrophotometric chemosensor

Abstract

Over the past few years, the relevance of ions and molecules with biological activity has increased. Search for new molecules capable of coordinating these analytes has gained interest in research. Thiosemicarbazones are an important member of N,S-donor ligands possessing versatile bonding modes, and biological applications as antiviral, antibacterial and anti-cancer. The complexing ability can be tuned by introducing substituents of different nature. Their potency as an intermediate to synthesize pharmaceutic and bioactive materials enhances their extensive application in the area of medicinal chemistry. The easy method of usage, ability for modulation and integration in different applications makes them versatile. Thiosemicarbazones are reported as chemosensors for different cations and anions.