Pub Date : 2025-11-06DOI: 10.1080/10426507.2025.2586128
Jiyao Dong (Investigation Supervision Writing – original draft) , Yuchao Cui (Data curation Formal analysis Supervision) , Dianting Gong (Data curation Investigation Supervision Writing – original draft) , Zhiwei Yao (Conceptualization Funding acquisition Writing – review & editing)
A series of MgO-supported cobalt phosphide catalysts (CoP-5, CoP-15, CoP-30, and CoP-45) with varying cobalt loadings (5–45 wt%) were synthesized for methane dry reforming (DRM). The CoP-30 showed the highest initial activity due to its optimal balance of Co loading, surface area and particle size, while CoP-45 exhibited superior long-term stability owing to enhanced coking resistance from a lower ratio of CH4 and CO2 dissociation rates. These findings provided insights for designing efficient and stable DRM catalysts.
{"title":"The effect of Co loading on the performance of Co2P/MgO catalysts for dry reforming of methane","authors":"Jiyao Dong (Investigation Supervision Writing – original draft) , Yuchao Cui (Data curation Formal analysis Supervision) , Dianting Gong (Data curation Investigation Supervision Writing – original draft) , Zhiwei Yao (Conceptualization Funding acquisition Writing – review & editing)","doi":"10.1080/10426507.2025.2586128","DOIUrl":"10.1080/10426507.2025.2586128","url":null,"abstract":"<div><div>A series of MgO-supported cobalt phosphide catalysts (CoP-5, CoP-15, CoP-30, and CoP-45) with varying cobalt loadings (5–45 wt%) were synthesized for methane dry reforming (DRM). The CoP-30 showed the highest initial activity due to its optimal balance of Co loading, surface area and particle size, while CoP-45 exhibited superior long-term stability owing to enhanced coking resistance from a lower ratio of CH<sub>4</sub> and CO<sub>2</sub> dissociation rates. These findings provided insights for designing efficient and stable DRM catalysts.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 128-135"},"PeriodicalIF":1.6,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this study, we report the synthesis and application of a novel basic nanocatalyst, ZS-DABCO NPs, prepared by functionalizing NaY nanozeolite with 3-chloropropyl trimethoxy silane followed by diazabicyclo[2.2.2]octane (DABCO). The catalyst was thoroughly characterized by FT-IR, XRD, CHN, DTA, TGA, TEM, and SEM analyses. ZS-DABCO NPs was successfully employed as an efficient and environmentally friendly catalyst for the one-pot, three-component synthesis of 2-amino-4H-chromene derivatives from dimedone, aromatic aldehydes, and malononitrile (or ethyl cyanoacetate) in ethanol under mild conditions. Optimization studies revealed that using 30 mg of catalyst in ethanol at room temperature provided the best yields, while comparative studies with other catalysts confirmed the superior performance of ZS-DABCO NPs in terms of yield, reaction time, and ease of recovery. The catalyst demonstrated excellent recyclability, maintaining its activity over six consecutive runs without significant loss of efficiency. Structural elucidation of the synthesized compounds was confirmed using NMR and IR spectroscopy. This work offers a simple, rapid, high-yielding, and green methodology for the synthesis of chromene derivatives, expanding the scope of clean organic transformations.
{"title":"One pot synthesis of chromene derivatives by using amine-functionalized nanozeolite (ZS-DABCO NPs) as a heterogeneous and reusable catalyst","authors":"Hamed Ghahremani (Funding acquisition Methodology) , Navabeh Nami (Conceptualization Data curation Formal analysis Investigation Methodology Project administration Software Supervision Writing – original draft Writing – review & editing) , Reza Yousefi (Data curation Formal analysis Investigation)","doi":"10.1080/10426507.2025.2585101","DOIUrl":"10.1080/10426507.2025.2585101","url":null,"abstract":"<div><div>In this study, we report the synthesis and application of a novel basic nanocatalyst, ZS-DABCO NPs, prepared by functionalizing NaY nanozeolite with 3-chloropropyl trimethoxy silane followed by diazabicyclo[2.2.2]octane (DABCO). The catalyst was thoroughly characterized by FT-IR, XRD, CHN, DTA, TGA, TEM, and SEM analyses. ZS-DABCO NPs was successfully employed as an efficient and environmentally friendly catalyst for the one-pot, three-component synthesis of 2-amino-4<em>H</em>-chromene derivatives from dimedone, aromatic aldehydes, and malononitrile (or ethyl cyanoacetate) in ethanol under mild conditions. Optimization studies revealed that using 30 mg of catalyst in ethanol at room temperature provided the best yields, while comparative studies with other catalysts confirmed the superior performance of ZS-DABCO NPs in terms of yield, reaction time, and ease of recovery. The catalyst demonstrated excellent recyclability, maintaining its activity over six consecutive runs without significant loss of efficiency. Structural elucidation of the synthesized compounds was confirmed using NMR and IR spectroscopy. This work offers a simple, rapid, high-yielding, and green methodology for the synthesis of chromene derivatives, expanding the scope of clean organic transformations.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 114-127"},"PeriodicalIF":1.6,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A green and efficient approach was developed for the synthesis of twenty-three α-aminophosphonate derivatives (4a-4v) via the Kabachnik–Fields reaction, using acetylsalicylic acid as a novel eco-friendly Brønsted acid catalyst under ultrasound irradiation and solvent-free conditions. The target compounds were obtained in moderate to excellent yields (43 - 91%) and were structurally characterized by FTIR, 1H NMR, 13C NMR, and single-crystal X-ray diffraction analysis. Notably, the crystal structure of compound 4c was elucidated by X-ray diffraction, providing detailed molecular and supramolecular insights. The antioxidant activity of the synthesized compounds was evaluated through four in vitro assays (DPPH, ABTS, FRAP, and phenanthroline), with compounds 4a, 4c, 4d, and 4k demonstrating significant potency. Additionally, antifungal activity was assessed against Fusarium oxysporum f. sp. lycopersici, with compound 4t exhibiting the highest inhibitory effect.
以乙酰水杨酸为催化剂，在超声辐照和无溶剂条件下，通过Kabachnik-Fields反应合成了23种α-氨基膦酸衍生物（4a-4v）。目标化合物的产率为43 ~ 91%，并通过FTIR、1H NMR、13C NMR和单晶x射线衍射分析对其进行了结构表征。值得注意的是，化合物4c的晶体结构通过x射线衍射被阐明，提供了详细的分子和超分子的见解。通过四种体外实验（DPPH、ABTS、FRAP和phenanthroline）评估合成化合物的抗氧化活性，化合物4a、4c、4d和4k显示出显著的效力。此外，化合物4t对番茄尖孢镰刀菌（Fusarium oxysporum f. sp. lycopersici）的抑菌活性也进行了评价，其中化合物4t抑菌效果最好。
{"title":"Ultrasound-promoted one-pot synthesis of α-aminophosphonates: X-ray crystallographic study and biological screening","authors":"Imene Sehout (Conceptualization Visualization) , Kawther Badaoui (Investigation Writing – original draft) , Hasan Kucukbay (Methodology Validation) , Sara Nemouchi (Investigation) , Lamia Bendjeddou (Investigation Validation Writing – original draft) , Chawki Bensouici (Investigation Validation) , Ali Debbi (Investigation) , Thierry Roisnel (Investigation Software) , Raouf Boulcina (Supervision) , Abdelmadjid Debache (Project administration)","doi":"10.1080/10426507.2025.2584184","DOIUrl":"10.1080/10426507.2025.2584184","url":null,"abstract":"<div><div>A green and efficient approach was developed for the synthesis of twenty-three α-aminophosphonate derivatives (<strong>4a</strong>-<strong>4v</strong>) <em>via</em> the Kabachnik–Fields reaction, using acetylsalicylic acid as a novel eco-friendly Brønsted acid catalyst under ultrasound irradiation and solvent-free conditions. The target compounds were obtained in moderate to excellent yields (43 - 91%) and were structurally characterized by FTIR, <sup>1</sup>H NMR, <sup>13</sup>C NMR, and single-crystal X-ray diffraction analysis. Notably, the crystal structure of compound <strong>4c</strong> was elucidated by X-ray diffraction, providing detailed molecular and supramolecular insights. The antioxidant activity of the synthesized compounds was evaluated through four <em>in vitro</em> assays (DPPH, ABTS, FRAP, and phenanthroline), with compounds <strong>4a</strong>, <strong>4c</strong>, <strong>4d</strong>, and <strong>4k</strong> demonstrating significant potency. Additionally, antifungal activity was assessed against <em>Fusarium oxysporum f. sp. lycopersici</em>, with compound <strong>4t</strong> exhibiting the highest inhibitory effect.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 96-109"},"PeriodicalIF":1.6,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-04DOI: 10.1080/10426507.2025.2584187
Egor I. Seleznev (Conceptualization Data curation Formal analysis Investigation Methodology Visualization Writing – original draft) , Emil Yu. Yamansarov (Conceptualization Data curation Project administration Supervision Writing – review & editing) , Elena K. Beloglazkina (Resources Supervision Writing – review & editing)
Substitution reactions of 1-halo-1-nitrocyclohexanes with thioglycolic acid and cysteine derivatives were investigated. Readily available 1-bromo-1-nitrocompounds exhibit good stability and superior reactivity compared to other halogenides, enabling the formation of corresponding α-nitrosulfides and disulfides.
{"title":"Investigation of the reactions of 1-halo-1-nitroocyclohexanes with some –SH functionalized carboxylic acids derivatives","authors":"Egor I. Seleznev (Conceptualization Data curation Formal analysis Investigation Methodology Visualization Writing – original draft) , Emil Yu. Yamansarov (Conceptualization Data curation Project administration Supervision Writing – review & editing) , Elena K. Beloglazkina (Resources Supervision Writing – review & editing)","doi":"10.1080/10426507.2025.2584187","DOIUrl":"10.1080/10426507.2025.2584187","url":null,"abstract":"<div><div>Substitution reactions of 1-halo-1-nitrocyclohexanes with thioglycolic acid and cysteine derivatives were investigated. Readily available 1-bromo-1-nitrocompounds exhibit good stability and superior reactivity compared to other halogenides, enabling the formation of corresponding α-nitrosulfides and disulfides.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 110-113"},"PeriodicalIF":1.6,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-03DOI: 10.1080/10426507.2025.2581743
Pei Li (Funding acquisition Project administration Writing – original draft Writing – review & editing) , Wenting Mei (Data curation Methodology Writing – original draft) , Yongxiang Wu (Data curation Methodology) , Wenmin Pan (Data curation Methodology Software) , You Zhang (Data curation Methodology Software) , Xiang Wang (Funding acquisition Project administration Writing – review & editing)
In this study, using the plant-derived active compound carvacrol as the lead structure, a series of carvacrol derivatives incorporating a thiosemicarbazide moiety were synthesized and their structures were characterized by 1H NMR,13C NMR, and HRMS. Subsequently, the in vitro antioxidant and α-glucosidase inhibitory activities of these compounds were evaluated. The bioassay results indicated that the target compounds exhibited certain in vitro antioxidant and α-glucosidase inhibitory activities. Among them, compound 2-(2-(5-isopropyl-2-methylphenoxy)acetyl)-N-phenylhydrazine-1-carbothioamide (4i) displayed the most potent in vitro antioxidant activity, with IC50 values of 4.98 μg/mL for DPPH scavenging activity and 2.34 μg/mL for ABTS scavenging activity, which were superior to those of vitamin C and trolox. Meanwhile, compound N-(4-fluorophenyl)-2-(2-(5-isopropyl-2-methylphenoxy)acetyl)hydrazine-1-carbothioamide (4j) exhibited excellent in vitro α-glucosidase inhibitory activity, with an IC50 value of 8.32 μg/mL, outperforming both carvacrol and acarbose.
本研究以植物源活性化合物香芹酚为先导结构，合成了一系列含有巯基氨基脲片段的香芹酚衍生物，并通过1H NMR、13C NMR和HRMS对其结构进行了表征。随后，评价了这些化合物的体外抗氧化活性和α-葡萄糖苷酶抑制活性。生物实验结果表明，目标化合物具有一定的体外抗氧化活性和α-葡萄糖苷酶抑制活性。其中，化合物2-（2-（5-异丙基-2-甲基苯氧基）乙酰基）- n -苯肼-1-碳硫酰胺（4i）的体外抗氧化活性最强，其清除DPPH的IC50值为4.98 μg/mL，清除ABTS的IC50值为2.34 μg/mL，均优于维生素C和trolox。同时，化合物N-（4-氟苯基）-2-（2-（5-异丙基-2-甲基苯氧基）乙酰基）肼-1-碳硫酰胺（4j）具有良好的体外α-葡萄糖苷酶抑制活性，IC50值为8.32 μg/mL，优于香芹酚和阿卡波糖。
{"title":"Novel carvacrol derivatives containing a thiosemicarbazide moiety: As potential antioxidants and α-glucosidase inhibitors","authors":"Pei Li (Funding acquisition Project administration Writing – original draft Writing – review & editing) , Wenting Mei (Data curation Methodology Writing – original draft) , Yongxiang Wu (Data curation Methodology) , Wenmin Pan (Data curation Methodology Software) , You Zhang (Data curation Methodology Software) , Xiang Wang (Funding acquisition Project administration Writing – review & editing)","doi":"10.1080/10426507.2025.2581743","DOIUrl":"10.1080/10426507.2025.2581743","url":null,"abstract":"<div><div>In this study, using the plant-derived active compound carvacrol as the lead structure, a series of carvacrol derivatives incorporating a thiosemicarbazide moiety were synthesized and their structures were characterized by <sup>1</sup>H NMR,<sup>13</sup>C NMR, and HRMS. Subsequently, the <em>in vitro</em> antioxidant and α-glucosidase inhibitory activities of these compounds were evaluated. The bioassay results indicated that the target compounds exhibited certain <em>in vitro</em> antioxidant and α-glucosidase inhibitory activities. Among them, compound 2-(2-(5-isopropyl-2-methylphenoxy)acetyl)-<em>N</em>-phenylhydrazine-1-carbothioamide (<strong>4i</strong>) displayed the most potent <em>in vitro</em> antioxidant activity, with IC<sub>50</sub> values of 4.98 μg/mL for DPPH scavenging activity and 2.34 μg/mL for ABTS scavenging activity, which were superior to those of vitamin C and trolox. Meanwhile, compound <em>N</em>-(4-fluorophenyl)-2-(2-(5-isopropyl-2-methylphenoxy)acetyl)hydrazine-1-carbothioamide (<strong>4j</strong>) exhibited excellent <em>in vitro</em> α-glucosidase inhibitory activity, with an IC<sub>50</sub> value of 8.32 μg/mL, outperforming both carvacrol and acarbose.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 45-50"},"PeriodicalIF":1.6,"publicationDate":"2025-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The effect of various electron-donating and electron-withdrawing substituents on the reactivity and mechanism of the McCormack [4 + 2] cycloaddition reaction was systematically investigated using density functional theory (DFT) at the M06-2X/6-311++G(2d,2p) level of theory. This reaction, an underexplored cheletropic process, involves the formation of phospholene oxides from substituted dienes and dihalophosphines. Conformational analysis revealed that the so-called “cis” dienes in experimental studies are more accurately described as gauche conformers. Conceptual DFT indices indicated that dienes act as nucleophiles, while dihalophosphines serve as electrophiles. Global electron density transfer (GEDT) values confirmed the non-polar nature of the transition states. The proposed two-step mechanism includes a slow cheletropic step followed by rapid hydrolysis, with the first step identified as the rate-determining step. Thermodynamic and kinetic analyses showed the exothermicity of the overall reaction, and isomerization pathways leading to 2-phospholene oxides were also explored. These findings provide detailed insight into substituent effects on the McCormack reaction and offer theoretical guidance for designing more efficient organophosphorus syntheses.
{"title":"DFT-based insight into substituent-controlled McCormack cycloaddition for the formation of phospholene oxides","authors":"Tayebeh Hadadi (Conceptualization Data curation Formal analysis Investigation Software) , Mehdi Shahraki (Investigation Methodology Software Supervision Writing – review & editing) , Fatemeh Mahmoudi (Data curation Formal analysis Methodology Visualization Writing – original draft)","doi":"10.1080/10426507.2025.2584183","DOIUrl":"10.1080/10426507.2025.2584183","url":null,"abstract":"<div><div>The effect of various electron-donating and electron-withdrawing substituents on the reactivity and mechanism of the McCormack [4 + 2] cycloaddition reaction was systematically investigated using density functional theory (DFT) at the M06-2X/6-311++G(2d,2p) level of theory. This reaction, an underexplored cheletropic process, involves the formation of phospholene oxides from substituted dienes and dihalophosphines. Conformational analysis revealed that the so-called “<em>cis</em>” dienes in experimental studies are more accurately described as <em>gauche</em> conformers. Conceptual DFT indices indicated that dienes act as nucleophiles, while dihalophosphines serve as electrophiles. Global electron density transfer (GEDT) values confirmed the non-polar nature of the transition states. The proposed two-step mechanism includes a slow cheletropic step followed by rapid hydrolysis, with the first step identified as the rate-determining step. Thermodynamic and kinetic analyses showed the exothermicity of the overall reaction, and isomerization pathways leading to 2-phospholene oxides were also explored. These findings provide detailed insight into substituent effects on the McCormack reaction and offer theoretical guidance for designing more efficient organophosphorus syntheses.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 85-95"},"PeriodicalIF":1.6,"publicationDate":"2025-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-31DOI: 10.1080/10426507.2025.2580370
Nitin Carpenter (Conceptualization Data curation Formal analysis Investigation Methodology Resources Software) , Navdeep Sharma (Conceptualization Data curation Formal analysis Funding acquisition Investigation Methodology Project administration Resources Software Validation Writing – original draft Writing – review & editing) , H. P. S. Chauhan (Supervision)
A series of new arsenic(III) bis(dithiocarbamate) complexes with mixed thio and oxo donor ligands were synthesized via a targeted replacement reaction using arsenic(III) bis(N,N’-diethyldithiocarbamato-S,S’) chloride as the precursor. The powder XRD revealed nano-sized crystalline domains (20.63–23.01 nm) and monoclinic symmetry with unit cell volumes ranging from 1269–1280 ų. In the ESI-MS spectra, specific fragmentation patterns indicated the selective loss of SOCCH3 and OOCCH3 in compounds 4 and 5, respectively, yielding a notable base peak at 371.0 m/z. Compound 6 (arsenic(III) bis(N,N’-diethyldithiocarbamato-S,S’) thiosalicylate) decomposed thermally to form stable arsenic sulfide, aligning well with the predicted elemental composition. Thermal stability was confirmed through TGA and DTG analysis. Functionally, the nano-scale and unique structural features of these complexes confer enhanced antimicrobial properties, outperforming both free ligands and standard drugs. Using chloramphenicol and terbinafine as references, these derivatives demonstrated significant inhibition zones, suggesting promising applications in antimicrobial therapeutics. This study not only expands the understanding of arsenic-based coordination complexes but also underscores their potential as bioactive materials in medicinal chemistry.
{"title":"Synthesis and integrated physicochemical–biological characterization of arsenic(III) bis(N,N′-diethyldithiocarbamato-S,S′) complexes with mixed thio and oxo donor ligands","authors":"Nitin Carpenter (Conceptualization Data curation Formal analysis Investigation Methodology Resources Software) , Navdeep Sharma (Conceptualization Data curation Formal analysis Funding acquisition Investigation Methodology Project administration Resources Software Validation Writing – original draft Writing – review & editing) , H. P. S. Chauhan (Supervision)","doi":"10.1080/10426507.2025.2580370","DOIUrl":"10.1080/10426507.2025.2580370","url":null,"abstract":"<div><div>A series of new arsenic(III) bis(dithiocarbamate) complexes with mixed thio and oxo donor ligands were synthesized <em>via</em> a targeted replacement reaction using arsenic(III) bis(N,N’-diethyldithiocarbamato-S,S’) chloride as the precursor. The powder XRD revealed nano-sized crystalline domains (20.63–23.01 nm) and monoclinic symmetry with unit cell volumes ranging from 1269–1280 Å<sup>³</sup>. In the ESI-MS spectra, specific fragmentation patterns indicated the selective loss of SOCCH<sub>3</sub> and OOCCH<sub>3</sub> in compounds 4 and 5, respectively, yielding a notable base peak at 371.0 m/z. Compound 6 (arsenic(III) bis(N,N’-diethyldithiocarbamato-S,S’) thiosalicylate) decomposed thermally to form stable arsenic sulfide, aligning well with the predicted elemental composition. Thermal stability was confirmed through TGA and DTG analysis. Functionally, the nano-scale and unique structural features of these complexes confer enhanced antimicrobial properties, outperforming both free ligands and standard drugs. Using chloramphenicol and terbinafine as references, these derivatives demonstrated significant inhibition zones, suggesting promising applications in antimicrobial therapeutics. This study not only expands the understanding of arsenic-based coordination complexes but also underscores their potential as bioactive materials in medicinal chemistry.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 74-84"},"PeriodicalIF":1.6,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
An efficient and green electrochemical trifluoromethylation of imidazo[2,1-b]thiazoles was realized by employing CF3SO2Na (Langlois reagent) as the CF3 source. The 2,3-dihydroimidazo[2,1-b]thiazoles, 2-phenylbenzo[d]imidazo[2,1-b]thiazole and 2-phenylimidazo[1,2-a]pyridine also worked well. The strategy provides regioselective C-5 trifluoromethylation products with broad scope in 56-88% yields. In addition, this trifluoromethylation process has the advantages of being chemical oxidant-free and metal-free under safe and mild reaction conditions.
{"title":"Electrochemical regioselective trifluoromethylation of imidazo[2,1-b]thiazoles with CF3SO2Na","authors":"Meilin Liu (Methodology Writing – original draft) , Meng Xiao (Methodology Writing – review & editing) , Peng Liao (Data curation Writing – review & editing) , Wenjie Liu (Investigation Project administration)","doi":"10.1080/10426507.2025.2580364","DOIUrl":"10.1080/10426507.2025.2580364","url":null,"abstract":"<div><div>An efficient and green electrochemical trifluoromethylation of imidazo[2,1-<em>b</em>]thiazoles was realized by employing CF<sub>3</sub>SO<sub>2</sub>Na (Langlois reagent) as the CF<sub>3</sub> source. The 2,3-dihydroimidazo[2,1-<em>b</em>]thiazoles, 2-phenylbenzo[d]imidazo[2,1-<em>b</em>]thiazole and 2-phenylimidazo[1,2-<em>a</em>]pyridine also worked well. The strategy provides regioselective C-5 trifluoromethylation products with broad scope in 56-88% yields. In addition, this trifluoromethylation process has the advantages of being chemical oxidant-free and metal-free under safe and mild reaction conditions.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 136-142"},"PeriodicalIF":1.6,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sustainable development goals (SDGs) determined by the United Nations have underlined the necessity of circular economy practices, and concerns have been accelerated to sustain a transition between linear economy model to circular practices to accomplish the aim by 2030. The effort on this field is simply summarized as utilization of natural resources should be minimized and residual waste utilization should be maximized. Phosphogypsum (PG) is the by-product generated in phosphate fertilizer production process. Annual generation capacity of PG has risen to 300 million tons, however the statistical data regarding further processing underlines that 14% of PG generated is being utilized for various applications. Currently, PG management route lies mostly on storage, and 58% of PG is stockpiled. The rest 28% portion is discharged to coastal areas. Increasing the circularity of PG within the compliance to circular economy practices has been intensively focused because most of PG’s structure is composed of calcium sulfate, which strengthens its resemblance to natural gypsum, the rest being rare earth elements and heavy metals as the impurities. PG management indicates that the material does not create urgent environmental risks, however research on this field recommends enhanced PG processing rate rather than stockpiling, and the potential of PG utilization as a substitute for natural gypsum has been intensively evaluated. Developing a utilization pathway as a secondary resource would help effective resource management within the compliance to SDGs. Therefore, this paper provides a comprehensive review for the management of PG from a general point of view by analyzing the critical points in recycling and discussing possible potential application areas.
{"title":"A comprehensive review on phosphogypsum management dynamics","authors":"Ertuğrul Çelik (Conceptualization Investigation Writing – review & editing) , Cemre Avşar (Investigation Writing – review & editing) , Suna Ertunç (Supervision Writing – review & editing)","doi":"10.1080/10426507.2025.2578202","DOIUrl":"10.1080/10426507.2025.2578202","url":null,"abstract":"<div><div>Sustainable development goals (SDGs) determined by the United Nations have underlined the necessity of circular economy practices, and concerns have been accelerated to sustain a transition between linear economy model to circular practices to accomplish the aim by 2030. The effort on this field is simply summarized as utilization of natural resources should be minimized and residual waste utilization should be maximized. Phosphogypsum (PG) is the by-product generated in phosphate fertilizer production process. Annual generation capacity of PG has risen to 300 million tons, however the statistical data regarding further processing underlines that 14% of PG generated is being utilized for various applications. Currently, PG management route lies mostly on storage, and 58% of PG is stockpiled. The rest 28% portion is discharged to coastal areas. Increasing the circularity of PG within the compliance to circular economy practices has been intensively focused because most of PG’s structure is composed of calcium sulfate, which strengthens its resemblance to natural gypsum, the rest being rare earth elements and heavy metals as the impurities. PG management indicates that the material does not create urgent environmental risks, however research on this field recommends enhanced PG processing rate rather than stockpiling, and the potential of PG utilization as a substitute for natural gypsum has been intensively evaluated. Developing a utilization pathway as a secondary resource would help effective resource management within the compliance to SDGs. Therefore, this paper provides a comprehensive review for the management of PG from a general point of view by analyzing the critical points in recycling and discussing possible potential application areas.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 1-23"},"PeriodicalIF":1.6,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Graph invariants, particularly topological indices, play a crucial role in understanding chemical structures. The face index, a recently introduced descriptor based on graph faces, predicts key physicochemical properties (e.g., energy levels, boiling points) but remains unexplored for oxide and silicate networks, a gap, that hinders its application to these industrially vital materials. Here, we derive exact closed form expressions for the face index of these networks, providing the first analytical formulas for these systems. Our results not only advance the mathematical characterization of complex silicates and oxides but also establish a foundation for correlating face index values with various physicochemical properties, enabling future QSAR/QSPR studies.
{"title":"On face index for some oxide and silicate networks","authors":"Jai Parkash (Conceptualization Formal analysis Validation Writing – original draft Writing – review & editing) , Vijay Kumar Bhat (Conceptualization Supervision Validation Writing – review & editing)","doi":"10.1080/10426507.2025.2578205","DOIUrl":"10.1080/10426507.2025.2578205","url":null,"abstract":"<div><div>Graph invariants, particularly topological indices, play a crucial role in understanding chemical structures. The face index, a recently introduced descriptor based on graph faces, predicts key physicochemical properties (e.g., energy levels, boiling points) but remains unexplored for oxide and silicate networks, a gap, that hinders its application to these industrially vital materials. Here, we derive exact closed form expressions for the face index of these networks, providing the first analytical formulas for these systems. Our results not only advance the mathematical characterization of complex silicates and oxides but also establish a foundation for correlating face index values with various physicochemical properties, enabling future QSAR/QSPR studies.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"201 1","pages":"Pages 65-73"},"PeriodicalIF":1.6,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145771944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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