Salusin-α attenuates lipid accumulation of C57BL/6 mice with Non-alcoholic fatty liver

Abstract

With the development of society and economy, Non-alcoholic fatty liver disease (NAFLD) has gradually affected people's health. It is very important to find an effective treatment for NAFLD. Salusin-α is a kind of cardiovascular active peptide that can reduce blood pressure and slow down the heart rate. Studies have shown that Salusin-α can inhibit the development of atherosclerosis by regulating lipid metabolism. However, whether Salusin-α can inhibit the lipid accumulation of C57BL/6 mice with NAFLD has not been reported. Our study found that Salusin-α ameliorated lipid accumulation of NAFLD mice. Salusin-α has a good prospect in the treatment of NAFLD.