Comparing the effect of ropivacaine peritonsillar injection before and after adenotonsillectomy on postoperative pain among pediatric patients: A double-blind randomized clinical trial

IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY International journal of pediatric otorhinolaryngology Pub Date : 2025-02-03 DOI:10.1016/j.ijporl.2025.112249
Mohammad Faramarzi , Ashkan Panah , Peyman Hassanpourhaghighi , Fatemeh Kanaani Nejad , Naeimehossadat Asmarian , Fatemeh Khalili , Soodabeh Emami , Fatane Jamshidi , Mahsa Emadi , Niloofar Borzou
{"title":"Comparing the effect of ropivacaine peritonsillar injection before and after adenotonsillectomy on postoperative pain among pediatric patients: A double-blind randomized clinical trial","authors":"Mohammad Faramarzi ,&nbsp;Ashkan Panah ,&nbsp;Peyman Hassanpourhaghighi ,&nbsp;Fatemeh Kanaani Nejad ,&nbsp;Naeimehossadat Asmarian ,&nbsp;Fatemeh Khalili ,&nbsp;Soodabeh Emami ,&nbsp;Fatane Jamshidi ,&nbsp;Mahsa Emadi ,&nbsp;Niloofar Borzou","doi":"10.1016/j.ijporl.2025.112249","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>Ropivacaine local injection is a preventative management option for post-adenotonsillectomy pain. The effectiveness of this approach varies depending on the time of drug administration. This study is aimed to evaluate pre-emptive effect of administration of Ropivacaine before vs. after adenotonsillectomy.</div></div><div><h3>Methods</h3><div>In this study, children aged 3–12 years who were diagnosed with chronic tonsillitis candidates for elective adenotonsillectomy surgery randomly assigned to one of three randomized groups. Participants in the first group got a peritonsillar injection of 3 mg/kg Ropivacaine 1 % before the surgery, patients in the second group received 3 mg/kg Ropivacaine 1 % peritonsillar injection after surgery, and patients in the control group received peritonsillar injections of 5 cc normal saline. Postoperative pain was assessed using the Wong-Baker Pain Scale. SPSS software was used to perform statistical analysis.</div></div><div><h3>Results</h3><div>Among total of 99 enrolled cases, mean age of 7.29 ± 2.61 years, participants who received Ropivacaine before surgery experienced significantly less postoperative pain four, eight, and 24 h after surgery (P = 0.001). In addition, compared to other groups, these patients consumed significantly less analgesics during postoperative hospitalization and after discharge (p &lt; 0.001 and = 0.001 respectively).</div></div><div><h3>Conclusion</h3><div>Ropivacaine peritonsillar injection before adenotonsillectomy may be more beneficial than Ropivacaine injection after surgery for postoperative pain management among children undergoing adenotonsillectomy.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"190 ","pages":"Article 112249"},"PeriodicalIF":1.2000,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of pediatric otorhinolaryngology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165587625000369","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives

Ropivacaine local injection is a preventative management option for post-adenotonsillectomy pain. The effectiveness of this approach varies depending on the time of drug administration. This study is aimed to evaluate pre-emptive effect of administration of Ropivacaine before vs. after adenotonsillectomy.

Methods

In this study, children aged 3–12 years who were diagnosed with chronic tonsillitis candidates for elective adenotonsillectomy surgery randomly assigned to one of three randomized groups. Participants in the first group got a peritonsillar injection of 3 mg/kg Ropivacaine 1 % before the surgery, patients in the second group received 3 mg/kg Ropivacaine 1 % peritonsillar injection after surgery, and patients in the control group received peritonsillar injections of 5 cc normal saline. Postoperative pain was assessed using the Wong-Baker Pain Scale. SPSS software was used to perform statistical analysis.

Results

Among total of 99 enrolled cases, mean age of 7.29 ± 2.61 years, participants who received Ropivacaine before surgery experienced significantly less postoperative pain four, eight, and 24 h after surgery (P = 0.001). In addition, compared to other groups, these patients consumed significantly less analgesics during postoperative hospitalization and after discharge (p < 0.001 and = 0.001 respectively).

Conclusion

Ropivacaine peritonsillar injection before adenotonsillectomy may be more beneficial than Ropivacaine injection after surgery for postoperative pain management among children undergoing adenotonsillectomy.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
3.20
自引率
6.70%
发文量
276
审稿时长
62 days
期刊介绍: The purpose of the International Journal of Pediatric Otorhinolaryngology is to concentrate and disseminate information concerning prevention, cure and care of otorhinolaryngological disorders in infants and children due to developmental, degenerative, infectious, neoplastic, traumatic, social, psychiatric and economic causes. The Journal provides a medium for clinical and basic contributions in all of the areas of pediatric otorhinolaryngology. This includes medical and surgical otology, bronchoesophagology, laryngology, rhinology, diseases of the head and neck, and disorders of communication, including voice, speech and language disorders.
期刊最新文献
Adenotonsillectomy success for treating obstructive sleep apnea in children with Prader-Willi syndrome Interventional treatment for juvenile recurrent parotitis: A 10-year experience in a tertiary centre Editorial Board The intricate interrelationship of cochlear aperture and internal auditory canal diameter in pediatric normal petrous structures Mutation spectrum of GJB2, SLC26A4 and mtDNA12SrRNA genes in non-syndromic hearing loss patients from Gansu, China
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1