{"title":"Improving Nursing Assessment and Early Identification of Ifosfamide-Related Toxicity in Patients With Cancer.","authors":"","doi":"10.1188/24.CJON.551-558","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy agents like ifosfamide can cause dose-limiting renal and central nervous system (CNS) toxicities. Routinely assessing for CNS changes associated with ifosfamide was not standard nursing practice, and the lack of provider and nursing knowledge of subtle CNS changes was identified as a safety factor that needed improving.</p><p><strong>Objectives: </strong>The purpose of this quality improvement project was to implement an evidence-based nursing assessment tool to provide early identification of ifosfamide toxicity.</p><p><strong>Methods: </strong>The project team created an internal tool incorporating the Common Terminology Criteria for Adverse Events to categorize and grade toxicity symptoms. Nurses used the tool to assess patients' renal and CNS baselines and monitor for 13 potential symptoms throughout ifosfamide administration.</p><p><strong>Findings: </strong>Acute care oncology nurses felt empowered to report subtle CNS changes when using the tool, leading to early identification of ifosfamide toxicity.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":"28 6","pages":"551-558"},"PeriodicalIF":1.2000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical journal of oncology nursing","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1188/24.CJON.551-558","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NURSING","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Chemotherapy agents like ifosfamide can cause dose-limiting renal and central nervous system (CNS) toxicities. Routinely assessing for CNS changes associated with ifosfamide was not standard nursing practice, and the lack of provider and nursing knowledge of subtle CNS changes was identified as a safety factor that needed improving.
Objectives: The purpose of this quality improvement project was to implement an evidence-based nursing assessment tool to provide early identification of ifosfamide toxicity.
Methods: The project team created an internal tool incorporating the Common Terminology Criteria for Adverse Events to categorize and grade toxicity symptoms. Nurses used the tool to assess patients' renal and CNS baselines and monitor for 13 potential symptoms throughout ifosfamide administration.
Findings: Acute care oncology nurses felt empowered to report subtle CNS changes when using the tool, leading to early identification of ifosfamide toxicity.
期刊介绍：
The Clinical Journal of Oncology Nursing (CJON) is an official publication of the Oncology Nursing Society (ONS) and is directed to the practicing nurse specializing in the care of patients with an actual or potential diagnosis of cancer. CJON is a vehicle to promote the mission of ONS, which is to advance excellence in oncology nursing and quality cancer care. The CJON mission is twofold: to provide practical information necessary to care for patients and their families across the cancer continuum and to develop publication skills in oncology nurses.
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