Discovery of drug targets for heart failure with preserved and reduced ejection fraction

IF 10.8 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Nature cardiovascular research Pub Date : 2025-02-06 DOI:10.1038/s44161-024-00605-x
Scott C. Ritchie
{"title":"Discovery of drug targets for heart failure with preserved and reduced ejection fraction","authors":"Scott C. Ritchie","doi":"10.1038/s44161-024-00605-x","DOIUrl":null,"url":null,"abstract":"Drug targets that are supported by human genetics are more likely to lead to approved therapies. Research now identifies several promising drug targets and therapeutic repurposing opportunities for heart failure and its clinical sub-types.","PeriodicalId":74245,"journal":{"name":"Nature cardiovascular research","volume":"4 3","pages":"254-255"},"PeriodicalIF":10.8000,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature cardiovascular research","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44161-024-00605-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

Abstract

Drug targets that are supported by human genetics are more likely to lead to approved therapies. Research now identifies several promising drug targets and therapeutic repurposing opportunities for heart failure and its clinical sub-types.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
发现具有保留和降低射血分数的心力衰竭药物靶点。
有人类遗传学支持的药物靶点更有可能导致获得批准的治疗方法。研究现在确定了几个有希望的药物靶点和治疗心力衰竭及其临床亚型的机会。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
5.70
自引率
0.00%
发文量
0
期刊最新文献
Genome-wide association study of coronary flow reserve assessed by cardiac perfusion PET suggests a role for NF-κB pathway. Lipoprotein(a) and oxidized phospholipids are associated with myocardial inflammation after acute myocardial infarction. Consensus statement on mass spectrometry-based proteomic analysis of cardiac tissue. CAMK2 inhibition treats genetic dilated cardiomyopathy in mice. Macrophages orchestrate the landscape of advanced cardiac allograft vasculopathy
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1