Correlation of retinal curvature with ocular biometry in patients with myopia

IF 2.6 3区医学 Q2 ONCOLOGY Photodiagnosis and Photodynamic Therapy Pub Date : 2025-04-01 Epub Date: 2025-02-04 DOI:10.1016/j.pdpdt.2025.104505

Guo-Ren Xu , Ming Yan , Zhen Huang , Ya Ye , Yan-Ping Song

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Abstract

Purpose

To evaluate the relationship between retinal curvature (RC) and ocular biometry in patients with myopia.

Method

The clinical data of 74 patients with myopia (148 eyes) were retrospectively analyzed. Macular 24×20 mm optical coherence tomography (OCT) scans were acquired using an ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) system. The software then identified the Bruch's membrane and integrated it with the axial length (AL) for morphological correction, yielding a fitted three-dimensional retinal model. From this model, an RC map was generated, detailing the Gaussian curvature at each point. The maximum retinal curvature (RCmax) and central macular retinal curvature (RCc) were analyzed.

Results

A total of 148 eyes were analyzed. The analysis revealed that RCmax was negatively correlated with AL (r=-0.266, P < 0.05) and positively correlated with mean keratometry (Km) (r = 0.285, P < 0.05). RCc was also positively correlated with Km (r = 0.167, P < 0.05), whereas RCmax and RCc were positively correlated with each other (r = 0.450, P < 0.05).

Conclusions

In eyes with large innate eyeballs (characterized by a smaller Km), the RCmax was smaller, and acquired axial elongation (characterized by a larger AL) led to a reduction in RCmax, and vice versa. Eyes with large innate eyeballs also showed a smaller RCc, and vice versa.

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近视患者视网膜曲率与眼部生物测量的相关性。

目的：探讨近视患者视网膜曲率（RC）与眼生物测量的关系。方法：回顾性分析74例（148眼）近视患者的临床资料。使用超宽视场扫描源光学相干断层扫描（UWF SS-OCT）系统获得黄斑24×20 mm光学相干断层扫描（OCT）。然后，该软件识别出布鲁赫膜，并将其与轴向长度（AL）结合起来进行形态学校正，生成一个合适的三维视网膜模型。从这个模型中，生成了一个RC地图，详细说明了每个点的高斯曲率。分析最大视网膜曲率（RCmax）和中央黄斑视网膜曲率（RCc）。结果：共分析了148只眼。结论：天生眼球较大（Km较小）的眼，RCmax较小，获得性轴向伸长（AL较大）导致RCmax减小，反之亦然。天生眼球较大的眼睛也显示出较小的RCc，反之亦然。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.