Advanced retinal disease detection from OCT images using a hybrid squeeze and excitation enhanced model.

IF 2.6 3区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES PLoS ONE Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI:10.1371/journal.pone.0318657
Gülcan Gencer, Kerem Gencer
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Abstract

Background: Retinal problems are critical because they can cause severe vision loss if not treated. Traditional methods for diagnosing retinal disorders often rely heavily on manual interpretation of optical coherence tomography (OCT) images, which can be time-consuming and dependent on the expertise of ophthalmologists. This leads to challenges in early diagnosis, especially as retinal diseases like diabetic macular edema (DME), Drusen, and Choroidal neovascularization (CNV) become more prevalent. OCT helps ophthalmologists diagnose patients more accurately by allowing for early detection. This paper offers a hybrid SE (Squeeze-and-Excitation)-Enhanced Hybrid Model for detecting retinal disorders from OCT images, including DME, Drusen, and CNV, using artificial intelligence and deep learning.

Methods: The model integrates SE blocks with EfficientNetB0 and Xception architectures, which provide high success in image classification tasks. EfficientNetB0 achieves high accuracy with fewer parameters through model scaling strategies, while Xception offers powerful feature extraction using deep separable convolutions. The combination of these architectures enhances both the efficiency and classification performance of the model, enabling more accurate detection of retinal disorders from OCT images. Additionally, SE blocks increase the representational ability of the network by adaptively recalibrating per-channel feature responses.

Results: The combined features from EfficientNetB0 and Xception are processed via fully connected layers and categorized using the Softmax algorithm. The methodology was tested on UCSD and Duke's OCT datasets and produced excellent results. The proposed SE-Improved Hybrid Model outperformed the current best-known approaches, with accuracy rates of 99.58% on the UCSD dataset and 99.18% on the Duke dataset.

Conclusion: These findings emphasize the model's ability to effectively diagnose retinal disorders using OCT images and indicate substantial promise for the development of computer-aided diagnostic tools in the field of ophthalmology.

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先进的视网膜疾病检测从OCT图像使用混合挤压和激励增强模型。
背景:视网膜问题非常重要,因为如果不及时治疗,它们会导致严重的视力丧失。诊断视网膜疾病的传统方法通常严重依赖于光学相干断层扫描(OCT)图像的人工解读,这既耗时又依赖于眼科医生的专业知识。这给早期诊断带来了挑战,尤其是当视网膜疾病如糖尿病性黄斑水肿(DME)、Drusen和脉络膜新生血管(CNV)变得越来越普遍时。通过允许早期发现,OCT帮助眼科医生更准确地诊断患者。本文提出了一种混合SE (Squeeze-and-Excitation)-Enhanced混合模型,用于从OCT图像中检测视网膜疾病,包括DME, Drusen和CNV,使用人工智能和深度学习。方法:该模型将SE块与effentnetb0和Xception架构相结合,在图像分类任务中取得了很高的成功率。effentnetb0通过模型缩放策略以更少的参数实现高精度,而Xception使用深度可分离卷积提供强大的特征提取。这些架构的结合提高了模型的效率和分类性能,能够更准确地从OCT图像中检测视网膜疾病。此外,SE块通过自适应地重新校准每个通道的特征响应来增加网络的表示能力。结果:来自EfficientNetB0和Xception的组合特征通过全连接层进行处理,并使用Softmax算法进行分类。该方法在加州大学圣地亚哥分校和杜克大学的OCT数据集上进行了测试,并产生了出色的结果。所提出的se改进混合模型优于当前最知名的方法,在UCSD数据集上的准确率为99.58%,在杜克数据集上的准确率为99.18%。结论:这些发现强调了该模型使用OCT图像有效诊断视网膜疾病的能力,并为眼科领域计算机辅助诊断工具的发展指明了实质性的希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
PLoS ONE
PLoS ONE 生物-生物学
CiteScore
6.20
自引率
5.40%
发文量
14242
审稿时长
3.7 months
期刊介绍: PLOS ONE is an international, peer-reviewed, open-access, online publication. PLOS ONE welcomes reports on primary research from any scientific discipline. It provides: * Open-access—freely accessible online, authors retain copyright * Fast publication times * Peer review by expert, practicing researchers * Post-publication tools to indicate quality and impact * Community-based dialogue on articles * Worldwide media coverage
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