Health-economic evaluation of the outpatient, inpatient, and public health sector in Germany: Insights from the first three COVID-19 waves.

IF 2.6 3区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES PLoS ONE Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI:10.1371/journal.pone.0314164
Afschin Gandjour
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Abstract

Aim: The aim of this study is to quantify the effectiveness and cost-effectiveness of the outpatient and inpatient sectors (specifically intensive care units, ICUs) and local health departments in managing the first three waves of the COVID-19 pandemic in Germany.

Methods: The analysis is based on a modelling approach using secondary data. The effectiveness of each sector was measured by determining the reduction in the case fatality rate (CFR) of COVID-19 patients by May 7, 2021. A counterfactual scenario assuming the absence of each sector was used to quantify their effectiveness. Direct medical costs for each sector were calculated from a statutory health insurance perspective, utilizing reimbursement rates for both the inpatient and outpatient sectors. Incremental cost-effectiveness ratios (ICERs) were determined, representing the costs per death avoided.

Results: The ICUs achieved the greatest reduction in the CFR of COVID-19 patients during the first three waves (1.9%). The outpatient sector followed with a reduction of 1.4%, and the local health departments contributed to a 0.3% decrease in the CFR. In terms of spending, ICUs had the highest expenditures among the sectors, resulting in an ICER of €59,055 per death avoided. On the other hand, local health departments were costlier but less effective than the outpatient sector. Results remained consistent across various input assumptions.

Conclusion: During the first three waves of the COVID-19 pandemic in Germany, the inpatient sector (ICUs) made the largest contribution to preventing deaths while also incurring the highest costs.

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德国门诊、住院和公共卫生部门的健康经济评估:来自前三波COVID-19的见解
目的:本研究的目的是量化门诊和住院部门(特别是重症监护病房,icu)和地方卫生部门在管理德国前三波COVID-19大流行方面的有效性和成本效益。方法:分析是基于使用二手数据的建模方法。通过确定到2021年5月7日COVID-19患者病死率(CFR)的降低来衡量每个部门的有效性。假设每个部门都不存在,使用反事实情景来量化其有效性。每个部门的直接医疗费用是从法定健康保险角度计算的,利用住院和门诊部门的报销率。确定增量成本-效果比(ICERs),代表每个避免死亡的成本。结果:前三波重症监护病房对COVID-19患者的CFR降低幅度最大(1.9%)。门诊部门紧随其后,减少了1.4%,地方卫生部门贡献了病死率下降0.3%。在支出方面,icu的支出在各部门中最高,每例避免死亡的成本为59 055欧元。另一方面,地方卫生部门比门诊部门成本更高,但效率更低。结果在不同的输入假设中保持一致。结论:在德国前三波COVID-19大流行期间,住院部门(icu)为预防死亡做出了最大贡献,同时也承担了最高的成本。
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来源期刊
PLoS ONE
PLoS ONE 生物-生物学
CiteScore
6.20
自引率
5.40%
发文量
14242
审稿时长
3.7 months
期刊介绍: PLOS ONE is an international, peer-reviewed, open-access, online publication. PLOS ONE welcomes reports on primary research from any scientific discipline. It provides: * Open-access—freely accessible online, authors retain copyright * Fast publication times * Peer review by expert, practicing researchers * Post-publication tools to indicate quality and impact * Community-based dialogue on articles * Worldwide media coverage
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