Somi Santharam Roja , P. Sneha Sunil , Muhammad Maqsood Darussalam , Vidhyashree Manoharan , John Prakash , Raju Ranjith Kumar
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引用次数: 0
Abstract
Copper (Cu) is essential for biological systems and animal-plant tissues, but Cu2+ ions are also significant environmental pollutants. An imbalance in non-toxic Cu2+ levels can lead to health issues. This study focuses on the development of a novel fluorescent turn-on probe, 3,4-dihydrobenzo[4,5]imidazole[2,1-b]quinazoline-1(2H)-one (HBQ) for the selective and sensitive detection of Cu2+ ions. The synthesis of HBQ was achieved from the reaction of 2-((dimethylamino)methylene)-cyclohexane-1,3-dione and 2-aminobenzimidazole. The photophysical properties of HBQ were investigated in various solvents. The strong binding of HBQ to Cu2+ causes a blue shift in the emission maxima and enhanced fluorescence due to reduced non-radiative decay, highlighting its selectivity for Cu2+ detection. Absorption and emission spectroscopy revealed the binding interactions, sensitivity, and selectivity of HBQ toward Cu2+ ions. The turn-on fluorescence of HBQ shows high sensitivity, with detection (LOD) and quantification (LOQ) limits extending to sub-micron concentrations. The sensor’s reliability and applicability were further validated using real samples, with a recovery rate of approximately 100 ± 2 %.
期刊介绍:
Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (SAA) is an interdisciplinary journal which spans from basic to applied aspects of optical spectroscopy in chemistry, medicine, biology, and materials science.
The journal publishes original scientific papers that feature high-quality spectroscopic data and analysis. From the broad range of optical spectroscopies, the emphasis is on electronic, vibrational or rotational spectra of molecules, rather than on spectroscopy based on magnetic moments.
Criteria for publication in SAA are novelty, uniqueness, and outstanding quality. Routine applications of spectroscopic techniques and computational methods are not appropriate.
Topics of particular interest of Spectrochimica Acta Part A include, but are not limited to:
Spectroscopy and dynamics of bioanalytical, biomedical, environmental, and atmospheric sciences,
Novel experimental techniques or instrumentation for molecular spectroscopy,
Novel theoretical and computational methods,
Novel applications in photochemistry and photobiology,
Novel interpretational approaches as well as advances in data analysis based on electronic or vibrational spectroscopy.