Exploring the homing effect and enhanced drug delivery potential of small extracellular vesicles†

IF 4.2 2区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Chemical Communications Pub Date : 2025-02-10 DOI:10.1039/D4CC06241H
Qi Zhang, Ke Cao, Ting-Ju Ren, Hao Wu and Zhang-Run Xu
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Abstract

We propose a strategy of assembling small extracellular vesicles (sEVs) and liposomes into dimers to explore the homing effect and the drug delivery potential of sEVs. The uptake rate of dimers by parental cells is 2.6–4.9 times higher than that by other cells, showing enhanced drug delivery capacity.

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探索细胞外小泡的归巢效应和增强的药物传递潜力。
我们提出了一种将细胞外囊泡(sev)和脂质体组装成二聚体的策略,以探索sev的归巢效应和药物递送潜力。亲本细胞对二聚体的摄取率比其他细胞高2.6 ~ 4.9倍,表现出增强的药物传递能力。
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来源期刊
Chemical Communications
Chemical Communications 化学-化学综合
CiteScore
8.60
自引率
4.10%
发文量
2705
审稿时长
1.4 months
期刊介绍: ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.
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