Exploring Current Diagnosis and Management of Amiodarone-induced Thyrotoxicosis

Abstract

Amiodarone, commonly used to treat various types of arrhythmias, can potentially lead to catastrophic adverse effects like amiodarone-induced thyrotoxicosis (AIT). This review offers insights into diagnosing and managing AIT, involving thyroid function tests, imaging techniques, and strategies to prevent cardiac deterioration and reduce mortality. The approach to managing AIT has shifted from focusing on thyrotoxicosis control to a broader strategy that includes preventing heart deterioration, hospitalizations, and reducing mortality. Healthcare professionals should consider the patient's need for amiodarone, side effects, coexisting conditions, and personal perspective. Routine thyroid function monitoring and collaboration across medical specialties are essential for comprehensive AIT management. Effective management of AIT is crucial to diminish mortality and morbidity. Pharmacological treatment can be initiated. Further intervention such as thyroidectomy is recommended, especially in cases where cardiac status is deteriorating and amiodarone continuation is necessary. In conclusion, early diagnosis and timely treatment through interdisciplinary collaboration according to specific individual case are crucial to reduce morbidity and mortality in AIT patients.