Evaluation of renal function in dogs using pulsed Doppler ultrasonography.

Abstract

Background: In human medicine, efforts have been made to evaluate venous blood flow in the kidneys to diagnose renal disease and estimate renal function. In dogs, previous studies have predicted renal function using the resistive index (RI) and pulsatility index (PI), which are derived from renal arterial blood flow velocity assessed via pulsed Doppler ultrasonography. However, to date, no study has been conducted on renal venous blood flow velocity in dogs.

Aim: To investigate the relationship between renal venous blood flow velocity and renal function.

Methods: Ten normal beagle dogs underwent blood tests and glomerular filtration rate (GFR) measurements. Pulsed Doppler ultrasonography was performed under sedation to measure the maximum venous flow velocity (Vmax), minimum venous flow velocity (Vmin), and venous impedance index in the renal and interlobular veins. The RI and PI were calculated from the renal and interlobular arteries.

Results: Vmax and Vmin of the renal vein were negatively correlated with GFR in both kidneys. No significant correlations were found between other measures and GFR. These results suggest a relationship between GFR and venous flow velocity in the renal veins assessed using pulsed Doppler ultrasonography.

Conclusion: These findings demonstrate the potential of this methodology as a new tool for predicting abnormalities in the renal venous blood flow and renal congestion in dogs. Further large-scale studies and comparisons between healthy dogs and dogs with impaired renal function are needed to validate this relationship.