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Phytochemicals, antioxidant, and antimicrobial activities of Opuntia stricta fruits peel. 狭叶桉果皮的植物化学物质、抗氧化剂和抗菌活性。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.14
Wissal Affi, Abdalla A Mohamed, Neji Gharsallah, Iryna Smetanska, Lazhar Zourgui

Background: Currently, research is focused on therapeutic plants which are regarded as a supply of several phytotherapeutic compounds with several activities; among these plants we find cacti.

Aim: The purpose of this work is to reveal the phytochemical composition and the antioxidant and antimicrobial properties of fruit peel from Opuntia stricta.

Methods: The phenolics profile has been obtained by liquid chromatography/electrospray ionization/mass spectroscopy analysis, antioxidant capacity has been evaluated by DPPH, FRAP, CAT, and ABTS• + free radical, and the antimicrobial activity was tested against 7 bacteria and 3 fungi.

Results: The results reveal that EFOS has a high content of polyphenols, flavonoids, quinic acid, and hyperoside which were the most dominant. Moreover, the observed antioxidant capacity of the extract was remarkable. In addition, a high antimicrobial capacity especially against Staphylococcus aureus and Pythium catenulatum. These results indicate that fruit peels of O. stricta have potential applications as a natural preservative in cosmetics and in food formulations, and also as a natural remedy.

Conclusion: The finding proved that EFOS is characterized first by a wide variability of polyphenols and flavonoids and secondly by good potential antioxidant and antibacterial activities.

背景:目的:本研究旨在揭示仙人掌果皮的植物化学成分以及抗氧化和抗菌特性:方法:通过液相色谱/电喷雾离子化/质谱分析获得酚类物质概况,通过 DPPH、FRAP、CAT 和 ABTS- + 自由基评估抗氧化能力,并对 7 种细菌和 3 种真菌进行抗菌活性测试:结果表明,EFOS 含有大量多酚、黄酮类化合物、奎宁酸和金丝桃苷,其中以奎宁酸和金丝桃苷的含量最高。此外,萃取物的抗氧化能力也非常显著。此外,果皮还具有很强的抗菌能力,尤其是对金黄色葡萄球菌和白锈菌的抗菌能力。这些结果表明,O. stricta 的果皮具有作为化妆品和食品配方中的天然防腐剂以及作为天然药物的潜在用途:研究结果证明,EFOS 的特点首先是多酚和类黄酮的多样性,其次是良好的潜在抗氧化和抗菌活性。
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引用次数: 0
Infectious bovine rhinotracheitis: Unveiling the hidden threat to livestock productivity and global trade. 传染性牛鼻气管炎:揭开对牲畜生产力和全球贸易的隐性威胁。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.3
Rimayanti Rimayanti, Aswin Rafif Khairullah, Tita Damayanti Lestari, Ikechukwu Benjamin Moses, Suzanita Utama, Ratna Damayanti, Sri Mulyati, Hartanto Mulyo Raharjo, Muhammad Khaliim Jati Kusala, Ricadonna Raissa, Syahputra Wibowo, Syafiadi Rizki Abdila, Kartika Afrida Fauzia, Sheila Marty Yanestria, Ima Fauziah, Josephine Elizabeth Siregar

An infectious disease called infectious bovine rhinotracheitis (IBR) can lead to a number of disorders affecting cattle's respiratory system. The disease is caused by bovine alphaherpesvirus type 1 (BoAHV-1). Based on antigenic and genetic characteristics, BoAHV-1 strains are divided into subtypes 1.1, 1.2a, 1.2b, and 1.3. IBR is currently widespread throughout the world, with the exception of a few nations that have achieved eradication. The most significant characteristic of this illness is that, after a clinical or subclinical infection, the virus typically establishes a latent condition that can later be reactivated in the presence of stress, immunosuppressive conditions/substances, or other diseases. Primarily, the virus spreads by direct or indirect contact between animals. It may also be transmitted via the reproductive system, causing infectious balanoposthitis or vulvovaginitis. Most virus subtypes are associated with reproductive failure, such as fetal or embryonic resorption and abortions. The virus may also be transmitted through semen, which could lead to genital transfer. Bovine herpesvirus type 1 (BoHV-1) infection produces a variety of lesions. Lesion in the mucosal surface usually consists of white necrotic material. Regular methods for diagnosing BoHV-1 infections include isolation in cell culture, enzyme linked immunosorbent assay, virus neutralisation test, and methods based on identification of nucleic acids, like PCR. The interplay of several host, pathogen, environmental, and management factors affects the spread of IBR. Through its impacts on health and fitness, IBR can lead to production losses. In order to minimize the severity of clinical signs and stop the infection from spreading, the veterinarian may advise that sick or at-risk animals be placed under immediate isolation and vaccinated (such as intranasal vaccination, including the use of both killed and live attenuated virus vaccines) as soon as an IBR diagnosis is obtained.

一种名为传染性牛鼻气管炎(IBR)的传染病可导致牛呼吸系统的一系列疾病。该病由牛α疱疹病毒 1 型(BoAHV-1)引起。根据抗原和基因特征,BoAHV-1 株系可分为 1.1、1.2a、1.2b 和 1.3 亚型。除少数国家已实现根除外,IBR 目前在全世界广泛流行。这种疾病的最大特点是,在临床或亚临床感染后,病毒通常会形成一种潜伏状态,随后在压力、免疫抑制条件/物质或其他疾病的作用下会重新激活。病毒主要通过动物之间的直接或间接接触传播。它也可能通过生殖系统传播,引起传染性包茎或外阴阴道炎。大多数病毒亚型与生殖系统衰竭有关,如胎儿或胚胎吸收和流产。病毒还可能通过精液传播,导致生殖器转移。牛疱疹病毒 1 型(BoHV-1)感染会产生多种病变。粘膜表面的病变通常由白色坏死物组成。诊断 BoHV-1 感染的常规方法包括细胞培养分离法、酶联免疫吸附试验、病毒中和试验以及基于核酸鉴定的方法(如 PCR)。宿主、病原体、环境和管理因素的相互作用影响着 IBR 的传播。通过对健康和体质的影响,IBR 可导致生产损失。为了将临床症状的严重程度降到最低并阻止感染扩散,兽医可能会建议将患病或有风险的动物立即隔离,并在确诊 IBR 后立即接种疫苗(如鼻内接种,包括使用灭活疫苗和减毒活疫苗)。
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引用次数: 0
Prevalence and risk factors associated with zoonotic gastrointestinal helminths transmitted by cats in Jabodetabek, Indonesia. 印度尼西亚 Jabodetabek 地区由猫传播的人畜共患胃肠道蠕虫的流行率和相关风险因素。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.5
Dyah Haryuningtyas Sawitri, April Hari Wardhana, Farlin Nefho, Eko Setyo Purwanto, Dwi Endrawati, Yudhi Ratna Nugraheni, Roza Azizah Primatika, Ndaru Andri Damayanti, Rizal Arifin Akbari, Eni Kusumaningtyas, Makoto Matsubayashi

Background: Intestinal helminth infections in cats are often neglected major zoonoses spread from pets to humans worldwide.

Aim: This study evaluated the prevalence and identified risk factors associated with zoonotic gastrointestinal helminth infections in different cat populations in the most populous megapolitan areas of Indonesia: Jakarta, Bogor, Depok, Tangerang, and Bekasi (Jabodetabek).

Methods: Fecal samples from the shelter (stray) and household (owned) cats were analyzed using sugar flotation techniques. Intestinal helminth eggs were detected microscopically based on structural and morphometric characteristics. Risk factors for the occurrence of helminth infection were identified through statistical analysis of cat ownership, breed, migrant status, management practices, caging, feed type, and deworming medications used. Human cases of worm larvae infestation identified during the interviews were reported.

Results: Analysis of 354 fecal samples revealed that 37.9% (134/354) of examined cats were infected with Toxocara sp., 22.6% (80/354) with Ancylostoma sp., 25.4% (90/354) with Uncinaria sp., 3.1% (11/354) with Strongyloides sp., 2% (7/354) with Diphyllobothrium sp., and 0.6% (2/354) with Dipylidium sp. Infection with roundworms and hookworms was associated with a variety of factors, including introduction of new animals, management practices, cage cleanliness, feed type, use of deworming medication, routine deworming, and contact with other animals. A human case of cutaneous larva migrans was due to hookworm (Ancylostoma sp./Uncinaria sp.) infection.

Conclusion: The prevalence of important zoonotic gastrointestinal nematodes (hookworms and roundworms) is high in cats in Jabodetabek, Indonesia. To reduce the risk of transmission to other animals or humans, adequate measures to control, manage, and prevent zoonotic helminth infections are required. This study presents important baseline information that provides a basis for future epidemiologic studies and the development of strategies to manage zoonotic gastrointestinal helminths in cats in the region.

背景:目的:本研究评估了印度尼西亚人口最多的大都市地区不同猫群中人畜共患胃肠道蠕虫感染的流行情况,并确定了相关风险因素:方法:方法:使用糖浮选技术分析收容所(流浪猫)和家庭(养猫)猫的粪便样本。根据结构和形态特征在显微镜下检测肠道蠕虫卵。通过对猫的所有权、品种、迁徙状况、管理方式、笼养、饲料类型和驱虫药物的统计分析,确定了发生蠕虫感染的风险因素。此外,还报告了在访谈中发现的人类蠕虫幼虫感染病例:对 354 份粪便样本的分析表明,37.9%(134/354)的受检猫感染了弓形虫,22.6%(80/354)感染了安氏弓形虫,25.4%(90/354)感染了钩端螺旋体,3.1%(11/354)感染了强氏弓形虫,2%(7/354)感染了双螺旋虫,0.6%(2/354)感染了疟原虫、蛔虫和钩虫感染与多种因素有关,包括引进新动物、管理方法、笼舍清洁度、饲料类型、驱虫药的使用、常规驱虫以及与其他动物的接触。一例人类皮肤幼虫移行症病例是由于钩虫(Ancylostoma sp./Uncinaria sp.)感染所致:结论:人畜共患的重要胃肠道线虫(钩虫和蛔虫)在印尼雅博迪塔贝克的猫中发病率很高。为了降低传染给其他动物或人类的风险,需要采取适当的措施来控制、管理和预防人畜共患病蠕虫感染。这项研究提供了重要的基础信息,为今后的流行病学研究和制定该地区猫的人畜共患胃肠蠕虫管理策略奠定了基础。
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引用次数: 0
Comparative efficacy of eugenol, eugenol nanoemulsion, and metronidazole against Trichomonas gallinae: An experimental study. 丁香酚、丁香酚纳米乳液和甲硝唑对加里宁毛滴虫的药效比较:实验研究。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.11
Abdollah Khaki, Mohamad Reza Youssefi, Nadia Taiefi Nasrabadi

Background: Trichomonas gallinae is a protozoan parasite responsible for canker in pigeons, a debilitating disease that causes significant economic losses. While metronidazole (MTZ) remains the primary treatment, the emergence of resistance is a growing concern. This study investigated the efficacy of eugenol and its nanoemulsion formulation against T. gallinae in both in vitro and in vivo settings.

Aim: To evaluate the anti-trichomonal activity of eugenol, eugenol nanoemulsion, and MTZ against T. gallinae using in vitro and in vivo models.

Methods: In vitro, T. gallinae trophozoites were exposed to varying concentrations of eugenol and eugenol nanoemulsion (0.625-10 μg/ml), as well as MTZ (25 μg/ml). Cytotoxicity was assessed using Vero cells. In vivo, 120 pigeons were experimentally infected and treated with either eugenol (10 mg/kg), eugenol nanoemulsion (10 mg/kg), MTZ (25 mg/kg), or left untreated. Treatments were administered daily for 5 days.

Results: In vitro, both eugenol and its nanoemulsion at 10 μg/ml achieved 100% lethality of T. gallinae after 48 hours, while MTZ reached the same effect within 24 hours. In vivo, MTZ and eugenol (at 25 mg/kg and 10 mg/kg, respectively) resulted in 100% recovery of infected pigeons 5 days post-treatment. Notably, eugenol nanoemulsion (10 mg/kg) achieved 100% recovery within just 4 days post-treatment.

Conclusion: This study highlights the potential of eugenol and its nanoemulsion as alternative treatments for T. gallinae infections in pigeons. The eugenol nanoemulsion, in particular, demonstrated promising results with faster recovery rates compared to both MTZ and eugenol, suggesting it may be especially effective against MTZ-resistant strains. Further research is warranted to explore the efficacy and safety of these agents for treating T. gallinae infections in pigeons.

背景:五倍子毛滴虫(Trichomonas gallinae)是一种原生动物寄生虫,是鸽子腐臭病的元凶,这种疾病会使鸽子衰弱,造成重大经济损失。虽然甲硝唑(MTZ)仍是主要的治疗方法,但抗药性的出现日益令人担忧。本研究调查了丁香酚及其纳米乳剂在体外和体内对五倍子蓟马的疗效。目的:使用体外和体内模型评估丁香酚、丁香酚纳米乳剂和 MTZ 对五倍子蓟马的抗滴虫活性:方法:在体外,将五倍子滋养体暴露于不同浓度的丁香酚和丁香酚纳米乳液(0.625-10 μg/ml)以及 MTZ(25 μg/ml)。使用 Vero 细胞评估细胞毒性。在体内,对 120 只鸽子进行实验性感染,并用丁香酚(10 毫克/千克)、丁香酚纳米乳剂(10 毫克/千克)、MTZ(25 毫克/千克)或不处理进行治疗。每天治疗一次,连续 5 天:结果:在体外,丁香酚及其纳米乳剂(10 μg/ml)在 48 小时后对五步蛇的致死率都达到了 100%,而 MTZ 在 24 小时内也达到了同样的效果。在体内,MTZ 和丁香酚(浓度分别为 25 毫克/千克和 10 毫克/千克)可使受感染的鸽子在治疗后 5 天内 100% 恢复健康。值得注意的是,丁香酚纳米乳剂(10 毫克/千克)可在治疗后 4 天内实现 100% 的痊愈:本研究强调了丁香酚及其纳米乳剂作为治疗鸽子五倍子疫霉菌感染的替代疗法的潜力。尤其是丁香酚纳米乳剂,与 MTZ 和丁香酚相比,其恢复速度更快,这表明它对 MTZ 耐药菌株尤其有效。我们需要进一步研究这些药物治疗鸽子五倍子疫病的有效性和安全性。
{"title":"Comparative efficacy of eugenol, eugenol nanoemulsion, and metronidazole against <i>Trichomonas gallinae</i>: An experimental study.","authors":"Abdollah Khaki, Mohamad Reza Youssefi, Nadia Taiefi Nasrabadi","doi":"10.5455/OVJ.2024.v14.i10.11","DOIUrl":"10.5455/OVJ.2024.v14.i10.11","url":null,"abstract":"<p><strong>Background: </strong><i>Trichomonas gallinae</i> is a protozoan parasite responsible for canker in pigeons, a debilitating disease that causes significant economic losses. While metronidazole (MTZ) remains the primary treatment, the emergence of resistance is a growing concern. This study investigated the efficacy of eugenol and its nanoemulsion formulation against <i>T. gallinae</i> in both <i>in vitro</i> and <i>in vivo</i> settings.</p><p><strong>Aim: </strong>To evaluate the anti-trichomonal activity of eugenol, eugenol nanoemulsion, and MTZ against <i>T. gallinae</i> using <i>in vitro</i> and <i>in vivo</i> models.</p><p><strong>Methods: </strong><i>In vitro</i>, <i>T. gallinae</i> trophozoites were exposed to varying concentrations of eugenol and eugenol nanoemulsion (0.625-10 μg/ml), as well as MTZ (25 μg/ml). Cytotoxicity was assessed using Vero cells. <i>In vivo</i>, 120 pigeons were experimentally infected and treated with either eugenol (10 mg/kg), eugenol nanoemulsion (10 mg/kg), MTZ (25 mg/kg), or left untreated. Treatments were administered daily for 5 days.</p><p><strong>Results: </strong><i>In vitro</i>, both eugenol and its nanoemulsion at 10 μg/ml achieved 100% lethality of <i>T. gallinae</i> after 48 hours, while MTZ reached the same effect within 24 hours. <i>In vivo</i>, MTZ and eugenol (at 25 mg/kg and 10 mg/kg, respectively) resulted in 100% recovery of infected pigeons 5 days post-treatment. Notably, eugenol nanoemulsion (10 mg/kg) achieved 100% recovery within just 4 days post-treatment.</p><p><strong>Conclusion: </strong>This study highlights the potential of eugenol and its nanoemulsion as alternative treatments for <i>T. gallinae</i> infections in pigeons. The eugenol nanoemulsion, in particular, demonstrated promising results with faster recovery rates compared to both MTZ and eugenol, suggesting it may be especially effective against MTZ-resistant strains. Further research is warranted to explore the efficacy and safety of these agents for treating <i>T. gallinae</i> infections in pigeons.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"14 10","pages":"2618-2627"},"PeriodicalIF":0.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11560258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142624888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune response and bacterial resistance of Oreochromis niloticus against bacterial fish pathogen with saffron diet. 用藏红花饲料喂养黑线鲈对细菌性鱼类病原体的免疫反应和细菌抵抗力。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.7
Heba A Tolba, Ahmed M Aldawek, Refaat A Eid, Sherine Aladdin, Nahla H El-Shaer

Background: The global demand for fish and fish products has increased due to population growth and healthier food choices. However, bacterial infections caused by Aeromonas species pose a challenge. Antibiotics are crucial for disease control, but multidrug resistance is a global concern. Eco-friendly disease management methods, like saffron, have been identified as potential treatments.

Aim: The study investigated the effects of dietary supplementation with Saffron on Nile tilapia's growth performance, immune response, and disease resistance.

Methods: 180 fish were acclimatized for 2 weeks and randomly allocated into three groups. The first group served as a control, while the other two groups were fed a basal diet supplemented with Saffron at 1.5 g/kg (T1) and 0.5 g/kg (T2), respectively, for 12 weeks. Biochemical blood parameters. Histopathology and immunohistochemical studies were performed on the gills, liver, and spleen tissues.

Results: Following the feeding trial with Saffron supplement, especially at higher levels enhanced weight gain, Growth performance, plasma total protein, and globulin showed higher levels in fish groups with dietary with Saffron at 1.5 g/kg (T1) and 0.5 g/kg (T2) than in fish fed the control diet Regulate the immune response in lysozyme activity and immunoglobulin M (IgM). Regeneration of gills, liver, and spleen tissues was noticed Furthermore, saffron-treated organs exhibited immunoreactivity to TNF-α was mostly seen in the liver and gills, although it was also somewhat in the kidney and spleen and CD68, the group were challenged with Aeromonas hydrophila, improved its defenses against A. hydrophila, immunity, and disease resistance than the control group.

Conclusion: The results showed that saffron supplementation significantly increased the survival rate of fish challenged with A. hydrophila. It also enhanced the immune response of fish, as evidenced by increased levels of serum immunoglobulins and lysozyme activity. These findings suggest that saffron supplementation could be a promising strategy for the prevention and treatment of bacterial infections in aquaculture.

背景:由于人口增长和更健康的食品选择,全球对鱼类和鱼类产品的需求有所增加。然而,由气单胞菌引起的细菌感染带来了挑战。抗生素对疾病控制至关重要,但多重耐药性是全球关注的问题。目的:本研究调查了膳食中补充藏红花对尼罗罗非鱼生长性能、免疫反应和抗病能力的影响。方法:180 尾鱼适应 2 周,随机分为三组。第一组为对照组,另外两组分别在基础饲料中添加 1.5 克/千克(T1)和 0.5 克/千克(T2)的藏红花,喂养 12 周。血液生化指标对鱼鳃、肝脏和脾脏组织进行了组织病理学和免疫组化研究:结果:在添加藏红花的饲养试验后,尤其是添加较高剂量的饲养试验后,添加 1.5 克/千克(T1)和 0.5 克/千克(T2)藏红花日粮的鱼类组的增重、生长性能、血浆总蛋白和球蛋白水平均高于对照组。此外,藏红花处理的器官对 TNF-α 的免疫反应主要见于肝脏和鳃,但在肾脏、脾脏和 CD68 中也有一定程度的表现,藏红花组在嗜水气单胞菌的挑战下,比对照组提高了对嗜水气单胞菌的防御能力、免疫能力和抗病能力:结果表明,添加藏红花能显著提高鱼类在嗜水气单胞菌挑战下的存活率。结论:结果表明,补充藏红花能明显提高鱼类对嗜水褐藻的存活率,同时还能增强鱼类的免疫反应,血清免疫球蛋白水平和溶菌酶活性的提高就证明了这一点。这些研究结果表明,补充藏红花是预防和治疗水产养殖中细菌感染的一种有效策略。
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引用次数: 0
Study of morphological and histological properties of the pancreas in crow (Linnaecus corvus) and Iraqi black partridge (Melanoperdix niger). 乌鸦(Linnaecus corvus)和伊拉克黑鹧鸪(Melanoperdix niger)胰腺形态和组织学特性研究。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.13
Rabab AbdAlameer Naser, Salah Hasan Almaliki, Fatimah Swadi Zghair, Ali Ibrahim Ali Al-Ezzy

Background: The structures of the pancreas in crow (Linnaecus corvus) and Iraqi black partridge (Melanoperdix niger) were the targets for histological and morphometric differences in both birds.

Aim: To study the comparative histomorphology of the pancreas in two species black partridge and local crow.

Methods: Five healthy black partridge and five local crows were used in the current study.

Results: The anatomical study reveals that the pancreas in both species is situated within the coelomic compartment on the right side. It is composed of four lobes including splenic, ventral, third, and dorsal lobes. It showed three ducts of the pancreas located between two duodenal limbs. Histologically, the pancreas of both birds contained two portions, endocrine and exocrine zone. The portion that occupied a large area of the pancreas was the exocrine which consisted of acini made of pyramid cells varying in shape and size. In black partridge, the acini have centroacinar cells but no centroacinar in crow. The duct system starting from the intercalated duct, interlobular and terminated by the main duct was folded with line simple columnar epithelium. The islet Langerhans was oval in black partridge and had a distinctive border containing two types of cells (Alpha and Beta), while a Delta, in addition to Alpha Beta cells, was detected in the crow islet Langerhans which was a sphincter in shape.

Conclusion: The pancreas of both bird black partridge (Melanoperdix niger) and crow (Linnaecus corvus) was a lobulated organ, that has a similar location in coelomic cavity. The pancreas in the crow was longer. In addition to the presence of some differences in histological structures between the two birds, a better understanding of the function of the pancreas in these species is needed.

背景:乌鸦(Linnaecus corvus)和伊拉克黑鹧鸪(Melanoperdix niger)的胰腺结构是两种鸟类组织学和形态学差异的目标:方法:本次研究使用了五只健康的黑鹧鸪和五只本地乌鸦:解剖学研究表明,两种乌鸦的胰腺都位于右侧的腹腔内。胰腺由四叶组成,包括脾叶、腹叶、第三叶和背叶。它的三个胰腺导管位于两个十二指肠肢之间。从组织学角度看,两只鸟的胰腺都包含两个部分,即内分泌区和外分泌区。占据胰腺大部分面积的部分是外分泌区,由形状和大小各异的金字塔细胞构成的针孔组成。黑鹧鸪的acini有中心acinar细胞,而乌鸦的acinar细胞没有中心acinar。导管系统从夹层导管、小叶间导管开始,以主导管为终点,折叠成简单的柱状上皮。黑鹧鸪的朗格汉斯小体呈椭圆形,有一个独特的边界,包含两种类型的细胞(Alpha 和 Beta),而乌鸦的朗格汉斯小体中除了 Alpha Beta 细胞外,还检测到一个 Delta 细胞,呈括约肌状:结论:黑鹧鸪(Melanoperdix niger)和乌鸦(Linnaecus corvus)的胰腺都是分叶状器官,在腹腔内的位置相似。乌鸦的胰腺更长。除了两种鸟的组织学结构存在一些差异外,还需要更好地了解这些物种的胰腺功能。
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引用次数: 0
A case of primary pulmonary paraganglioma in a dog. 一例狗的原发性肺副神经节瘤。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.22
Yoshimichi Goda, Shinya Mizutani, Natsuki Akashi, Teppei Kanda, Kenji Kutara, Yasuhiko Okamura, Taketoshi Asanuma

Background: Lung tumors in dogs, significantly primary paragangliomas, are rare and have not been reported. This report describes a dog with a lung tumor diagnosed as a primary paraganglioma.

Case description: A 12-year-old spayed French bulldog presented with a left-sided pulmonary mass. The dog was in good general condition and had no clinical symptoms. Computed tomography (CT) revealed a pulmonary mass near the bifurcation of the posterior lobe bronchus of the left lung. The mass showed a strong contrast enhancement effect that was subsequently attenuated. The dog underwent Surgery to remove the mass from the left lung. Abnormal hypertension was observed during surgery, and hypertensive crisis was suspected. Based on the histopathology and preoperative and postoperative urinary metanephrine and normetanephrine levels, the dog was diagnosed with primary paraganglioma of the lung. Although the CT scan showed findings suggestive of the development of a neuroendocrine tumor, it was difficult to suspect the development of a paraganglioma.

Conclusion: The possibility of catecholamine-producing tumors should be considered when we encounter a lung tumor with no clinical symptoms and a neuroendocrine tumor-like contrast enhancement pattern on a CT scan.

背景:狗的肺部肿瘤,尤其是原发性副神经节瘤,非常罕见,且尚未见报道。本报告描述了一只被诊断为原发性副神经节瘤的肺肿瘤犬:病例描述:一只 12 岁的法国斗牛犬因左侧肺部肿块前来就诊。该犬全身状况良好,没有任何临床症状。计算机断层扫描(CT)显示,左肺后叶支气管分叉处附近有一个肺肿块。肿块显示出强烈的对比度增强效应,随后有所减弱。该犬接受了切除左肺肿块的手术。手术过程中观察到异常高血压,怀疑是高血压危象。根据组织病理学、术前和术后尿液中的甲肾上腺素和常肾上腺素水平,该犬被诊断为原发性肺副神经节瘤。虽然 CT 扫描结果显示有神经内分泌肿瘤的迹象,但很难怀疑是副神经节瘤:结论:当我们遇到无临床症状、CT 扫描显示类似神经内分泌肿瘤造影剂增强模式的肺部肿瘤时,应考虑儿茶酚胺肿瘤的可能性。
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引用次数: 0
Factors influencing survival time in dogs with lymphoma: Correspondence. 影响淋巴瘤患犬存活时间的因素:通信。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.23
Hinpetch Daungsupawong, Viroj Wiwanitkit
{"title":"Factors influencing survival time in dogs with lymphoma: Correspondence.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.5455/OVJ.2024.v14.i10.23","DOIUrl":"10.5455/OVJ.2024.v14.i10.23","url":null,"abstract":"","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"14 10","pages":"2721"},"PeriodicalIF":0.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11560266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142624891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute phase proteins patterns as biomarkers in bacterial infection: Recent insights. 作为细菌感染生物标志物的急性期蛋白模式:最新见解。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.4
Amer Al Ali, Wageh Sobhy Darwish

Escherichia coli is a bacterium with command and pathogenic variants. It has been implicated in the induction of several inflammatory conditions. Finding a biomarker for infection began many years ago. The challenge of using acute phase proteins (APPs) as biomarkers for infection is a promising target for many researchers in this field. Many APPs have been studied for their roles as biomarkers of E. coli infection. The following review aims to highlight recent trials that have approved the use of adiponectin, amyloid A, ceruloplasmin, C-reactive protein, Haptoglobin, and Pentraxin 3 as biomarkers for E. coli infection and assess the obtained results. In conclusion, despite the existing approaches for the use of APPs as biomarkers in E. coli infection, we recommend more precise studies to enable these markers to be more specific and applicable in clinical fields. APPs could be markers for systemic inflammatory conditions, regardless of the causative agent.

大肠杆菌是一种细菌,有命令型和致病型变种。它与多种炎症的诱发有关。寻找感染的生物标志物始于多年前。利用急性期蛋白(APPs)作为感染的生物标志物是这一领域许多研究人员的一个有希望的目标。许多 APP 已被研究用作大肠杆菌感染的生物标志物。下面的综述旨在重点介绍最近批准使用脂肪连蛋白、淀粉样蛋白 A、脑磷脂蛋白、C 反应蛋白、Haptoglobin 和 Pentraxin 3 作为大肠杆菌感染生物标志物的试验,并对所取得的结果进行评估。总之,尽管目前已有将 APPs 用作大肠杆菌感染生物标志物的方法,但我们建议进行更精确的研究,以使这些标志物更具特异性并适用于临床领域。无论致病菌是什么,APPs 都可以作为全身性炎症的标志物。
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引用次数: 0
Classical swine fever: Unveiling the complexity through a multifaceted approach. 典型猪瘟:通过多层面方法揭示复杂性。
IF 0.9 Q3 VETERINARY SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI: 10.5455/OVJ.2024.v14.i10.1
Aswin Rafif Khairullah, Mustofa Helmi Effendi, Ikechukwu Benjamin Moses, Kartika Afrida Fauzia, Yulianna Puspitasari, Katty Hendriana Priscilia Riwu, Ima Fauziah, Ricadonna Raissa, Otto Sahat Martua Silaen, Syahputra Wibowo, Sheila Marty Yanestria, Muhammad Khaliim Jati Kusala, Syafiadi Rizki Abdila, Bima Putra Pratama, Abdullah Hasib

Classical swine fever (CSF), sometimes referred to as hog cholera, is a highly contagious, virally based, systemic illness that affects both domestic and wild pigs. The virus known as classical swine fever virus (CSFV) is a member of the Flaviviridae family, specifically the genus Pestivirus. This disease is thought to be endemic in many Asian countries that produce pork as well as in several countries in Central and South America, the Caribbean, and elsewhere. As previously indicated, depending on the virulence of the virus strain involved and several host circumstances, clinical indications of CSFV infection can vary greatly, ranging from abrupt fatality to an occult course. CSF diagnosis can be made by serological detection, antigen, RNA, and isolation. CSF's highly varied symptoms and post-mortem pathology resemble those of African swine fever (ASF). ASF, the kind of CSFV, the pig's age, and its susceptibility all affect the clinical symptoms. Pigs that contract CSFV, a highly infectious and economically significant virus. The great economic significance of the swine business makes the CSFV a potential bioterrorism threat. Live attenuated CSF vaccinations have been around for many years and are quite safe and effective. Controlling epidemics in CSFV-free zones requires quick action. Pigs that are impacted must be slaughtered, and the carcasses must be buried or burned.

猪瘟(CSF)有时也被称为猪霍乱,是一种高度传染性、病毒性、全身性疾病,家猪和野猪都会感染。被称为猪瘟病毒(CSFV)的病毒属于黄病毒科,特别是猪瘟病毒属。这种疾病被认为在许多生产猪肉的亚洲国家以及中南美洲、加勒比海和其他地区的一些国家流行。如前所述,根据相关病毒株的毒力和宿主的不同情况,CSFV 感染的临床表现会有很大差异,从突然死亡到隐性病程不等。CSF 的诊断可通过血清学检测、抗原、RNA 和分离来进行。CSF 的症状和死后病理变化与非洲猪瘟(ASF)非常相似。ASF、CSFV 的种类、猪的年龄及其易感性都会影响临床症状。感染 CSFV 病毒的猪具有高度传染性和经济意义。猪业的巨大经济意义使 CSFV 成为潜在的生物恐怖主义威胁。CSF 减毒活疫苗已经问世多年,非常安全有效。在无 CSFV 地区控制流行病需要迅速采取行动。受影响的猪必须宰杀,尸体必须掩埋或焚烧。
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引用次数: 0
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Open Veterinary Journal
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