Phototherapy in lymphoproliferative and inflammatory diseases associated with human T-lymphotropic virus.

IF 1.9 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-02-10 DOI:10.1093/trstmh/traf009

Brena Andrade de Lima Lobato, João Augusto Gomes de Souza Monteiro de Brito, José Maria de Castro Abreu Junior, Maísa Silva de Sousa, Carlos Augusto Moreira Silva, Thiago Xavier Carneiro, Rita Catarina Medeiros Sousa, Marília Brasil Xavier

{"title":"Phototherapy in lymphoproliferative and inflammatory diseases associated with human T-lymphotropic virus.","authors":"Brena Andrade de Lima Lobato, João Augusto Gomes de Souza Monteiro de Brito, José Maria de Castro Abreu Junior, Maísa Silva de Sousa, Carlos Augusto Moreira Silva, Thiago Xavier Carneiro, Rita Catarina Medeiros Sousa, Marília Brasil Xavier","doi":"10.1093/trstmh/traf009","DOIUrl":null,"url":null,"abstract":"Background: Dermatological manifestations affect 5% of patients with human T-lymphotropic virus (HTLV).Methods: Thirteen patients with inflammatory or lymphoproliferative dermatological diseases, both HTLV-positive and HTLV-negative, were selected for treatment with ultraviolet B narrowband (UVB-NB) phototherapy. Clinical and histopathological evaluations were conducted before and after 120 d of phototherapy.Results: All seven HTLV-positive patients evaluated were type 1. Clinical evaluation showed improvement in all 13 patients. In the histopathological examination, all patients with lymphoproliferative diseases and five with inflammatory diseases showed regression in most of the assessed parameters.Conclusions: The present research suggests that UVB-NB phototherapy is a promising treatment for lymphoproliferative and inflammatory skin diseases in HTLV-1 patients.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transactions of The Royal Society of Tropical Medicine and Hygiene","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/trstmh/traf009","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Dermatological manifestations affect 5% of patients with human T-lymphotropic virus (HTLV).

Methods: Thirteen patients with inflammatory or lymphoproliferative dermatological diseases, both HTLV-positive and HTLV-negative, were selected for treatment with ultraviolet B narrowband (UVB-NB) phototherapy. Clinical and histopathological evaluations were conducted before and after 120 d of phototherapy.

Results: All seven HTLV-positive patients evaluated were type 1. Clinical evaluation showed improvement in all 13 patients. In the histopathological examination, all patients with lymphoproliferative diseases and five with inflammatory diseases showed regression in most of the assessed parameters.

Conclusions: The present research suggests that UVB-NB phototherapy is a promising treatment for lymphoproliferative and inflammatory skin diseases in HTLV-1 patients.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

求助全文

约1分钟内获得全文去求助

来源期刊

Transactions of The Royal Society of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.00

自引率

9.10%

发文量

115

审稿时长

4-8 weeks

期刊介绍： Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.