Comparative Evaluation of Dentin Hypersensitivity Reduction Over One Month after a Single Topical Application of Three Different Materials: A Prospective Experimental Study.

IF 0.9 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-12-01 Epub Date: 2024-10-29 DOI:10.4103/jpbs.jpbs_848_24
Aniket Sharan, Babita Pawar, Hiroj Bagde, Tavinder Kaur Chawla, Aadarsh Vikram Dhan, Bhawna Shyamsukha, Sanjna Sharma
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Abstract

Background: Dentinal hypersensitivity (DH) is a prevalent condition characterized by sharp, transient pain arising from exposed dentine in response to various stimuli. It is common among patients with gingival recession, tooth abrasion, and erosion.

Materials and methods: A prospective experimental study was conducted in the Department of Periodontology at the Chhattisgarh Dental College and Research Institute. A total of 45 patients with DH were randomly assigned to three groups: Test Group I (5% potassium nitrate gel), Test Group II (Tetric-N-Bond self-etch adhesive), and Test Group III (fluoride varnish). Clinical assessments of DH were conducted immediately after treatment, at one week, and at one month, using tactile sensation, cold stimuli, and air blast tests. Pain levels were measured using a 10-point visual analog scale (VAS).

Results: Tetric-N-Bond demonstrated the most significant reduction in DH at all follow-up intervals. Immediately after application, VAS scores (tactile) were potassium nitrate (1.33 ± 0.48), Tetric-N-Bond (1.53 ± 0.74), and fluoride varnish (3.06 ± 0.88). After one month, the scores were: Tetric-N-Bond (2.53 ± 1.12), potassium nitrate (3.20 ± 0.41), and fluoride varnish (4.73 ± 1.57). Significant differences were observed between all groups (P < 0.05). The Schiff cold air score also supported these findings, showing Tetric-N-Bond as the most effective treatment, followed by potassium nitrate and fluoride varnish.

Conclusion: The study concluded that Tetric-N-Bond is the most effective treatment for reducing DH immediately and over a one-month period, followed by potassium nitrate and fluoride varnish.

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一项前瞻性实验研究:单次局部应用三种不同材料后一个月内牙本质过敏减少的比较评估。
背景:牙本质过敏(DH)是一种常见的疾病,其特征是由于暴露的牙本质对各种刺激的反应而引起尖锐的、短暂的疼痛。它常见于牙龈萎缩,牙齿磨损和侵蚀的患者。材料和方法:在恰蒂斯加尔邦牙科学院和研究所牙周病科进行了一项前瞻性实验研究。将45例DH患者随机分为3组:试验I组(5%硝酸钾凝胶)、试验II组(Tetric-N-Bond自蚀刻胶)和试验III组(氟清漆)。在治疗后立即、一周和一个月对DH进行临床评估,使用触觉、冷刺激和空气爆炸试验。疼痛水平采用10分视觉模拟量表(VAS)测量。结果:在所有随访期间,Tetric-N-Bond均表现出最显著的DH降低。应用后即刻VAS(触觉)评分为硝酸钾(1.33±0.48),tetrici - n - bond(1.53±0.74),氟清漆(3.06±0.88)。1个月后,评分为:Tetric-N-Bond(2.53±1.12)分、硝酸钾(3.20±0.41)分、氟化物清漆(4.73±1.57)分。各组间差异有统计学意义(P < 0.05)。希夫冷空气评分也支持了这些发现,显示tetrtic - n - bond是最有效的治疗方法,其次是硝酸钾和氟化物清漆。结论:该研究得出结论,tetrici - n - bond是立即和一个月内减少DH最有效的治疗方法,其次是硝酸钾和氟化物清漆。
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