Diagnostic Accuracy of MDCT Coronary Angiography in Patients with Ischemic Heart Disease.

IF 0.9 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-12-01 Epub Date: 2024-11-21 DOI:10.4103/jpbs.jpbs_1111_24
Arti Kumari, Suresh Kumar Toppo, Prakash Kumar, Rajeev Kumar Ranjan, Anima R Xalxo, Nisha Rai, Harsha Kaur
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Abstract

Introduction: One of the main causes of illness and death in both India and globally is coronary artery disease, or CAD. Previously, the majority of conventional catheter examinations were performed simply for diagnostic purposes. So, a noninvasive and trustworthy method was highly desirable for early CAD detection and coronary artery imaging.

Material and methods: Symptomatic patients attending the routine cardiac outpatient department at RIMS, Ranchi, who were advised to undergo coronary CT angiography (CCTA) for further evaluation in the Department of Radiodiagnosis were included.

Results: A total of 101 symptomatic patients were studied for patency of coronary vessels in both CCTA and conventional coronary angiography. Based on the CCTA of the 101 patients, majority of the patients belong to single vessel disease. CCTA revealed 124 lesions, of which 101 were considered serious with a majority of lesions in the left anterior descending. The sensitivity, specificity, positive predictive value, and negative predictive value of the multidetector computed tomography were 98.4, 91.7, 95, and 97.05%.

Conclusion: CCTA is a good negative predictive value technique for coronary stenosis and is relatively trustworthy.

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MDCT冠状动脉造影对缺血性心脏病诊断的准确性。
导言:在印度和全球疾病和死亡的主要原因之一是冠状动脉疾病,或CAD。以前,大多数常规导管检查仅用于诊断目的。因此,一种无创且可靠的方法对于早期CAD检测和冠状动脉成像是非常可取的。材料和方法:纳入了在Ranchi RIMS常规心脏门诊就诊的有症状的患者,这些患者被建议在放射诊断科接受冠状动脉CT血管造影(CCTA)进行进一步评估。结果:对101例有症状的患者进行CCTA和常规冠状动脉造影检查冠脉通畅情况。101例患者的CCTA显示,大多数患者属于单血管病变。CCTA显示124个病变,其中101个为严重病变,大多数病变位于左前降区。多探测器计算机断层扫描的敏感性、特异性、阳性预测值和阴性预测值分别为98.4、91.7、95%和97.05%。结论:CCTA是一种较好的冠状动脉狭窄阴性预测技术,具有较高的可信度。
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