Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-Analysis.

IF 0.9 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-12-01 Epub Date: 2024-11-29 DOI:10.4103/jpbs.jpbs_967_24
B Kanagasabapathy, Shubham Sharma, Piyush Dua, Nikil K Jain, V Preethi, Monika
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Abstract

The study aimed to evaluate soft tissue changes resulting from orthognathic surgery, specifically LeFort osteotomy, and distraction osteogenesis, in individuals with cleft lip and palate (CLP) suffering from midface hypoplasia. Following PRISMA guidelines, eight papers met inclusion criteria, with six providing quantitative data for meta-analysis. Notably, significant improvements were observed in both hard and soft tissues, particularly with horizontal maxillary advancement. Overall, orthognathic surgery positively influenced soft tissue profiles, especially the combination of LeFort osteotomy and sagittal split osteotomy. Moreover, maxillary distraction osteogenesis demonstrated superior soft tissue changes compared to LeFort I osteotomy alone, suggesting avenues for further research and potential enhancements.

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唇腭裂III级矫正术后各种正颌手术对软组织变化的评价:系统综述和meta分析。
该研究旨在评估患有中脸发育不全的唇腭裂(CLP)患者进行正颌手术(特别是LeFort截骨术)和牵张成骨术后软组织的变化。遵循PRISMA指南,8篇论文符合纳入标准,其中6篇提供了用于meta分析的定量数据。值得注意的是,软硬组织均有显著改善,特别是上颌水平前移。总的来说,正颌手术对软组织轮廓有积极的影响,尤其是LeFort截骨术和矢状劈开截骨术的结合。此外,上颌牵张成骨术与单独的LeFort I截骨术相比,显示出更好的软组织改变,这为进一步的研究和潜在的增强提供了途径。
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