Triglyceride-Glucose Index and its Relationship to Erectile Dysfunction in Subjects without Heart Disease.

IF 0.9 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-12-01 Epub Date: 2024-12-27 DOI:10.4103/jpbs.jpbs_1395_24
Sudeep Jayaram, S Santhosh, Nikhil Vaidya, Arifa Bakerywala, Harsh Anadkat, Heena Shaikh
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Abstract

Aim: This study primarily focused on evaluating the triglyceride-glucose (TyG) index in patients experiencing erectile dysfunction (ED) and examining its potential role as a predictive tool in diagnosing ED.

Materials and methods: The study involved a cohort of 50 patients diagnosed with erectile dysfunction, forming the study group, alongside 50 individuals exhibiting normal sexual function, who served as the control group. The assessment of erectile function was conducted using the International Index of Erectile Function-5 (IIEF-5) questionnaire. All participants underwent the calculation of the TyG index.

Results: The examination indicated that there were no notable disparities between the two groups regarding smoking rates, alcohol intake, or measurements of high-density lipoprotein cholesterol, haemoglobin, creatinine levels, and leukocyte and platelet counts. Individuals experiencing erectile dysfunction were found to be older and exhibited significantly higher levels of total cholesterol, low-density lipoprotein cholesterol, glucose, triglycerides, and the TyG index compared to the control group.

Conclusion: I n patients with erectile dysfunction, the TyG index-a simple test for insulin resistance (IR) -was found to be predictive.

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无心脏病受试者的甘油三酯-葡萄糖指数及其与勃起功能障碍的关系
目的:本研究主要关注于评估勃起功能障碍(ED)患者的甘油三酯-葡萄糖(TyG)指数,并探讨其作为ED诊断预测工具的潜在作用。材料和方法:本研究纳入了50名诊断为勃起功能障碍的患者,组成研究组,同时50名性功能正常的患者作为对照组。使用国际勃起功能指数5 (IIEF-5)问卷对勃起功能进行评估。所有参与者都进行了TyG指数的计算。结果:检查表明两组之间在吸烟率、酒精摄入量、高密度脂蛋白胆固醇、血红蛋白、肌酐水平、白细胞和血小板计数方面没有显著差异。与对照组相比,经历勃起功能障碍的个体年龄更大,总胆固醇、低密度脂蛋白胆固醇、葡萄糖、甘油三酯和TyG指数水平明显更高。结论:在勃起功能障碍患者中,TyG指数-一种简单的胰岛素抵抗(IR)测试-被发现具有预测性。
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