Hao-Tian Wang, Xin-Ting Qin, Bo Jiang, Prof. Dr. Zhi-Chao Chen, Prof. Dr. Wei Du, Prof. Dr. Ying-Chun Chen
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引用次数: 0
Abstract
Here we demonstrate that a Pt0 complex can function as an efficient π-Lewis base catalyst to increase the nucleophilicity of deactivated heteroarenes upon η2-coordination and resultant π-backdonation, thus enabling asymmetric Friedel-Crafts reaction with electrophiles. A diversity of densely functionalized adducts are produced in high yields with moderate to excellent enantioselectivity. Preliminary frontier molecular orbital (FMO) calculations and in situ 1H NMR analysis support the Pt0 π-Lewis base catalytic mode.
期刊介绍：
The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies.
The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry:
Liebigs Annalen
Bulletin des Sociétés Chimiques Belges
Bulletin de la Société Chimique de France
Gazzetta Chimica Italiana
Recueil des Travaux Chimiques des Pays-Bas
Anales de Química
Chimika Chronika
Revista Portuguesa de Química
ACH—Models in Chemistry
Polish Journal of Chemistry.
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